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Topical Antibiotics Mupirocin CAS 12650-69-0 Bactroban for Skin Infections Treatment

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  Post Date: Sep 30,2017
  Expiry Date: Sep 30,2018
  Detailed Description:
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pharmaceutical intermediate Skin Treatment CAS 12650-69-0 Antibiotics Mupirocin
Mupirocin is an antibacterial cream/ointment which is used to treat small areas of skin infection. It is sometimes used to treat infections such as impetigo in children. It works by killing the germs (bacteria) causing the infection.Mupirocin is used to treat certain skin infections (such as impetigo). It is an antibiotic. It works by stopping the growth of certain bacteria.

1. Quick Details:
Product name: Mupirocin,Bactroban
Mupirocin CAS: 12650-69-0
Mupirocin EINECS: 231-791-2
Mupirocin MF: C26H44O9
Mupirocin MW: 500.62
Mupirocin Density: 1.183 g/cm3
Mupirocin Purity: 99% min
Mupirocin Appearance: White Crystalline Solid
Mupirocin Boiling Point: 672.3ºCat 760 mmHg
Mupirocin Melting Point: 77-78ºC
Mupirocin Flash Point: 216.5 ºC
Mupirocin Storage Temp: Store cool, dark and dry
Mupirocin Refractive index: 1.524
Mupirocin Solubility: H2O: 12 mg/mL, soluble

2. Description of Mupirocin:
Mupirocin (trade names Bactroban, Centany) is an antibiotic. It is used topically and is effective against Gram-positive bacteria, including MRSA.Mupirocin is inactive for most anaerobic bacteria, mycobacteria, mycoplasma, chlamydia, yeast and fungi.
Mupirocin is bacteriostatic at low concentrations and bactericidal at high concentrations.It is of the monoxycarbolic acid class.Mupirocin is a mixture of several pseudomonic acids, with pseudomonic acid A (PA-A) constituting greater than 90% of the mixture. Also present in mupirocin are pseudomonic acid B with an additional hydroxyl group at C8,pseudomonic acid C with a double bond between C10 and C11, instead of the epoxide of PA-A,and pseudomonic acid D with a double bond at C4` and C5` in the 9-hydroxy-nonanoic acid portion of mupirocin.

3. Mupirocin Medical Uses:
Mupirocin is used as a topical treatment for bacterial skin infections, for example, furuncle,impetigo, open wounds, etc. It is also useful in the treatment of methicillin-resistantStaphylococcus aureus (MRSA), which is a significant cause of death in hospitalized patients having received systemic antibiotic therapy. It is suggested, however, that mupirocin cannot be used for extended periods of time, or indiscriminately, as resistance does develop, and could, if it becomes widespread, destroy mupirocin's value as a treatment for MRSA. It may also result in overgrowth of non-susceptible organisms.

4. How to Use Mupirocin:
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about the preparation prescribed for you.


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