Topotecan Hydrochloride
Post Date: |
Apr 07,2021 |
Expiry Date: |
Apr 07,2022 |
Detailed Description: |
Cas No. :119413-54-6
Quantity: 1Kilograms
Topotecan Hydrochloride is the water-soluble hydrochloride salt preparation of Topotecan, a potent inhibitor of topoisomerase 1, and an apoptosis inducer, producing proapoptotic and antiproliferative effects. Topotecan is a semisynthetic derivative of the natural product alkaloid camptothecin. It is described to stabilize topoisomerase I/DNA cleavable complexes and promote rapid apoptotic cell death in radiation-resistant human B-lineage acute lymphoblastic leukemia cells.
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CAS Registry Number: |
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Synonyms: |
;(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Nogitecan hydrochloride; Hycamtin;Topotecan HCl;(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride (1:1);(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(S)-10-((Dimethylamino)Methyl)-4-Ethyl-4,9-Dihydroxy-1H-Pyrano[3',4':6,7]Indolizino[1,2-B]Quinoline-3,14(4H,12H)-Dione Hydrochloride; |
Molecular Formula: |
C23H23N3O5 |
Molecular Weight: |
421.4458 |
Molecular Structure: |
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