Vitamin B12
Inquiry
| Post Date: | May 26,2016 |
| Expiry Date: | May 26,2017 |
| Detailed Description: |
Cas No. :68-19-9
Quantity: 1000Kilograms Specs:Cyanocobalamine Payment Method: T/T,LC Description Cyanocobalamine ,Vitamin B12, vitamin B12 or vitamin B-12, also called cobalamin, is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. Quality: excellent grade. Vitamin B12 consists of a class of chemically-related compounds (vitamers), all of which have vitamin activity. It contains the biochemically rare element cobalt. Vitamin B12, is used to treat vitamin B12 deficiency, cyanide poisoning, and hereditary deficiency of transcobalamin II. It is also given as part of the schilling test for detecting pernicious anemia. For cyanide poisoning, a large amount may be given intravenously, and sometimes in combination with sodium thiosulfate. The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine. In the United States, the Food and Drug Administration approved (in 2006) the use of hydroxocobalamin for acute treatment of cyanide poisoning. High vitamin B12 level in elderly individuals may protect against brain atrophy or shrinkage, associated with Alzheimer's disease and impaired cognitive function. High-dose administration of Vitamin B12 has been additionally validated to stimulate the activity of the body's TH1 suppressor T-Cells, which then down-regulates the over-production of the allergen antibody IgE in allergic individuals. Analyse Item Standard Appearance Dark red crystalline powder Identification Positive A361nm/A278nm:1.70-1.90 A361nm/A550nm:3.15-3.45 Loss on drying (%) ≤12.0 Assay 96.0-102.0 Related substances(%) ≤3 B12 Pseudo Cyanocobalamin Complies Medical uses Vitamin B12 is used to treat vitamin B12 deficiency, cyanide poisoning, and hereditary deficiency of transcobalamin II.It is also given as part of the Schilling test for detecting pernicious anemia. For cyanide poisoning, a large amount may be given intravenously, and sometimes in combination with sodium thiosulfate.The mechanism of action is straightforward: the hydroxycobalamin hydroxide ligand is displaced by the toxic cyanide ion, and the resulting harmless B12 complex is excreted in urine. In the United States, the Food and Drug Administration approved (in 2006) the use of hydroxocobalamin for acute treatment of cyanide poisoning. High vitamin B12 level in elderly individuals may protect against brain atrophy or shrinkage, associated with Alzheimer's disease and impaired cognitive function. High-dose administration of Vitamin B12 has been additionally validated to stimulate the activity of the body's TH1 suppressor T-Cells, which then down-regulates the over-production of the allergen antibody IgE in allergic individuals. Storage Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8 °C Contact information Daisy Sun Email: daisy@sybiological.com Hebei Shunyang Biological Technology CO., LTD Address:Room 1707, Zhukai Building, Youyi North Street, Shijiazhuang City Tel: 0086-311-80689350 Fax: 0086-311-87245305 Mob:86 18332425305 |
| CAS Registry Number: | 68-19-9 |
| Synonyms: | ;cyano-5,6-dimethylbenzimidazole-cobalamin;Cyanocobalamin;VB12;5,6-dimethyl-1-(3-o-phosphono-alpha-d-ribofuranosyl)-1h-benzimidazolmonoes; |
| Molecular Formula: | C63H88CoN14O14P |
| Molecular Weight: | 1355.3652 |
| Molecular Structure: | 
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| Safety Description: | S24/25:; |
| Company: | Hebei Shunyang Biological Technology CO., LTD [ China ] |
| Contact: | daisy |
| Tel: | 86-311-80689350 |
| Fax: | 86-311-87245305 |
| Email: | daisy@sybiological.com |
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