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everytihng about Coluracetam
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Post Date: | Apr 11,2016 |
Expiry Date: | Oct 08,2016 |
Detailed Description: |
Cas No. :135463-81-9
Specs:Purity:99% Payment Method: Western union,Money gram,Bank transfer,Paypal Coluracetam Keywords:nootropics Piracetam,Aniracetam,Pramiracetam,Oxiracetam, Coluracetam,Phenylpiracetam smart drugs Piracetam,Aniracetam, Pramiracetam,Oxiracetam,Coluracetam,Phenylpiracetam hot sale nootropics CAS No:135463-81-9 Purity:99% Appearance:white crystalline powder Package:1kg/bag. Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury. Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system. |
CAS Registry Number: | 135463-81-9 |
Synonyms: | N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide |
Molecular Formula: | C19H23N3O3 |
Molecular Weight: | 341.4042 |
Molecular Structure: |
Company: | Koffee Pharm company [ China ] |
Contact: | sophia simith |
Tel: | +86-21-61729394 |
Fax: | 86-21-61729394 |
Email: | sophia.koffeepharm@gmail.com |
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