134404-52-7;Seocalcitol

Post Date:
Jan 23,2013
Expiry Date:
Jan 23,2014
Detailed Description:
Cas No. :134404-52-7 Specs:10mg;100mg

Seocalcitol (EB 1089; EB-1089)is a Vitamin D receptor (VDR) agonist; Seocalcitol is a analog of calcitriol. Seocalcitol(EB 1089; EB-1089) exhibits anti-tumor and anti-proliferative activity with reduced hypercalcemic effects. 60 times more potent in inhibiting MCF-7 cell growth in vitro. Reverses the effects of parathyroid hormone-related protein (PTHrP)......
http://www.chemscene.com/Seocalcitol.html
CAS Registry Number:
134404-52-7
Synonyms:
Seocalcitol [INN:BAN];EB 1089;(5Z,7E,22E,24E)-24a,26a,27a-Trihomo-9,10-secocholesta-5,7,10(19),22,24-pentaene-1alpha,3beta,25-triol;1(S),3(R)-Dihydroxy-20(R)-(5'-ethyl-5'-hydroxyhepta-1'(E),3'(E)-dien-1'-yl)-9,10-secopregna-5(Z),7(E),10(19)-triene;1,3-Cyclohexanediol, 5-((2E)-((1R,3aS,7aR)-1-((1R,2E,4E)-6-ethyl-6-hydroxy-1-methyl-2,4-octadienyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-, (1R,3S,5Z)-;EB-1089;1,3-Cyclohexanediol, 5-((1-(6-ethyl-6-hydroxy-1-methyl-2,4-octadienyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-, (1R-(1alpha(1R*,2E,4E),3abeta,4E(1R*,3S*,5Z),7aalpha))-;(1R,3S,5E)-5-[(2Z)-2-{(1R,3aS,7aR)-1-[(1R,2E,4E)-6-ethyl-6-hydroxy-1-methylocta-2,4-dien-1-yl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexane-1,3-diol (non-preferred name);
Molecular Formula:
C₃₀H₄₆O₃
Molecular Weight:
454.6844
Molecular Structure:

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