3-Bromocinnamic acid

• Post Date:

  Dec 18,2019

• Expiry Date:

  Dec 17,2020

• Detailed Description:

  Cas No. :32862-97-8 Synonyms：RARECHEM BK HC T307; TRANS-3-BROMOCINNAMIC ACID; M-BROMOCINNAMIC ACID; M-BROMOPHENYLACRYLIC ACID;BROMOCINNAMIC ACID,3-;3-BROMOCINNAMIC ACID; AKOS BBS-00006566; AKOS B004044
  CAS NO.：32862-97-8
  Formula：C9H7BrO2
  Molecular weight: 227.05
  EINECS NO.:251-267-7
  Melting point: 177-179 °C
  Appearance: Colorless crystal
  Vapor pressure: 0.0±0.8 mmHg at 25°C
  Refractive index: 1.648
  Storage: Shading, confined preservation, dry, ensure good ventilation or exhaust in the workshop
  Stability: Stable under normal temperature and pressure
  Key words: 3-Bromocinnamic acid, spices, essence, Synthetic essence,
  
  General description
  3-Bromocinnamic acid is the metabolite of cinromide (3-bromo-N-ethylcinnamamide) and can be analysed in plasma by high-performance liquid chromatographic method.
  Simultaneous determination of the anticonvulsants, cinromide (3-bromo-n-ethylcinnamamide), 3-bromocinnamamide, and carbamazepine in plasma by high-performance liquid chromatography.
  3-Bromocinnamic acid is used as organic synthesis of raw materials, fine chemicals, pharmaceutical intermediates.
  
  Abstract
  A high-performance liquid chromatographic method is described for monitoring plasma concentrations of cinromide (3-bromo-N-ethylcinnamamide) and its de-ethylated metabolite. Carbamazepine levels can be easily measured by the same technique. The N-isopropyl analogue of cinromide is used as internal standard, and all compounds are easily separated on a reversed-phase column operated at 55 degrees with a small-diameter pre-column maintained at the same temperature. The extraction is rapid and generally applicable to plasma and urine samples that are to be analyzed by reversed-phase chromatography. Short- and long-term reproducibility studies show less than 4% relative standard deviation for replicate determinations for all drugs. Limits of quantitation are 10-20 ng/ml with an internal standard concentration of 3 micrograms/ml. Another metabolite of cinromide, 3-bromocinnamic acid, which may have some anticonvulsant effect, can be analyzed simultaneously by buffering the mobile phase and adding an ion-pairing reagent. Storage: Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.

• CAS Registry Number:

  32862-97-8

• Synonyms:

  ;(2E)-3-(3-bromophenyl)acrylic acid;3-(3-bromophenyl)prop-2-enoic acid;(2E)-3-(3-bromophenyl)prop-2-enoic acid;(2Z)-3-(3-bromophenyl)prop-2-enoic acid;(2E)-3-(3-bromophenyl)prop-2-enoate;m-Bromocinnamic acid;

• Molecular Formula:

  C₉H₆BrO₂

• Molecular Weight:

  226.0473

• Molecular Structure:

  

• Hazard Symbols:

   Xi:Irritant;
  

• Risk Codes:

  R36/37/38:;
  

• Safety Description:

  S26:;
  S36:;
  

• Company:

  Wuhan LANDMARK Industrial Co., Ltd     [ China ]        

• Contact:

  Halsey

• Tel:

  18062529653

• Fax:

• Email:

  Halsey.lmd@gmail.com