99% Purity Ropivacaine Mesylate for Local Anaesthesia CAS 854056-07-8
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Post Date:
Nov 20,2017
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Expiry Date:
Nov 20,2018
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Detailed Description:
Cas No. :854056-07-8
Quantity: 1000Kilograms
Specs:foil bag
Price:1 USD Kilograms
Payment Method: Western Union, money gram, t/t, bitcoin
99% Purity Ropivacaine Mesylate for Local Anaesthesia CAS 854056-07-8
Basic info.
Product name Ropivacaine mesylate
Synonyms (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide monomethanesulfonate;(S)-Ropivacaine Mesilate
CAS 854056-07-8
Assay 99.5%
M.F. C18H30N2O4S
M.W. 370.5068
Appearance White crystalline powder
Ropivacaine Mesylate Description
Ropivacaine Mesylate is a new long-acting amide local anesthetic, as a pure isomer, with anesthesia and analgesic dual role, high concentration can produce surgical anesthesia, low concentration can effectively block the sensory nerve conduction and motor nerve. Its pharmacological properties for cardiac toxicity is low, sensory block separation is more obvious, there is vasoconstriction, so no need to add adrenaline. Clinical mainly for surgical anesthesia, local anesthesia and acute pain control.
Ropivacaine Mesylate Application
1. Ropivacaine Mesylate for topical anesthesia, including infants infants aged 12 years or older, with nerve block, epidural and intrathecal anesthesia. It also represents 1 to 12 years old pain in children with peripheral nerve block and tail epidural pain. It is also sometimes used for surgical pain in children with anesthesia.
2. Ropivacaine Mesylate is usually combined with fentanyl for epidural analgesia, such as pregnant women, bupivacaine, usually intravenous liposomes, which are effective for treating animals. The experiment was secondary to local anesthetic overdose of severe cardiotoxicity in humans called Lipid Rescue.
COA
Items
Specification
Results
Description
White or practically white crystalline powder
White crystalline powder
Specific Rotation
30°~-35°
32°
Melting Range
232~239°C, and melting range is not more then 4°C
234~238°C
identification
It complies with the test for specific optical rotation and melting point
Conforms
Infrared absorption spectrophotometry should be consistent with levonorgestrel CRS
Conforms
Loss on drying
≤0.5%
0.20%
Residue on ignition
≤0.3%
0.07%
Limit of Ethynyl Group
7.81%~8.18%
7.92%
Related substances
Single impurity ≤0.5%
single impurity<0.5%
Total Impurities ≤2.0%
Total impurities<2.0%
Organic Volatile impurties
Ethanol ≤5000ppm
1200ppm
Assay The product complies with specification in USP34
Usage:
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).
Related Products:
Local Anesthetic
Formestane
L-Thyroxine / Epinephrine Hydrochloride
Duagen / Dutasteride
Finasteride / Prostide
Procaine Hydrochloride
Lidocaine
Lidocaine Hydrochloride
Tetracaine
Tetracaine Hydrochloride
Prilocaine
Articaine Hydrochloride
Levobupivacaine Hydrochloride Benzocaine / Ethyl 4-Aminobenzoate
Benzocaine Hydrochloride
Procaine
Procaine Hydrochloride
Propitocaine Hydrochloride
Pramoxine Hydrochloride
Proparacaine Hydrochloride
Dyclonine Hydrochloride
Dibucaine Hydrochloride
Bupivacaine Hydrochloride
Ropivacaine Mesylate
Paracetamol
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CAS Registry Number:
854056-07-8
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Synonyms:
;(2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide monomethanesulfonate;(S)-Ropivacaine Mesilate;S-Ropivacaine mesylate;
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Molecular Formula:
C18H30N2O4S
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Molecular Weight:
370.5068
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Molecular Structure:
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Company:
Hengyang Desen Biotechnology Co., Ltd.
[ China ]
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