99% USP 136-47-0 Tetracaine HCl/Tetracaine Hydrochloride

• Post Date:

  Aug 02,2016

• Expiry Date:

  Aug 02,2017

• Detailed Description:

  Cas No. :136-47-0 Price:1 USD Kilograms
  Payment Method: T/T,MONEYGRAM;WESTERNUNIOION
  99% USP 136-47-0 Tetracaine HCl/Tetracaine Hydrochloride
  Tetracaine HCl
  Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride;
  4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride
  CAS NO.: 136-47-0
  EINECS: 205-248-5
  MF: C15H25ClN2O2
  MW: 300.82
  MS:99% USP 136-47-0 Tetracaine HCl/Tetracaine Hydrochloride
  
  Melting point: 149°C
  Assay: 99%
  Grade: Pharmaceutical Grade
  Storage: Closed, confined and shading preservation
  Manufacturer: Simeiquan
  Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.
  
  Description:
  
  Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
  
  Application:
  
  Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
  In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
  
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  Test Items Specification Test Results
  Appearance Fine, white, crystalline, odorless powder confirm
  Identification ABC in Pass confirm
  Solubility Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene confirm
  USP Reference standards USP Tetracaine Hydrochloride RS. USP Endotoxin RS. confirm
  Melting point 145~150 degree 146.0~147.5 degree
  Chromatographic purity In Pass confirm
  Related substance Not more than the reference solution 0.05% confirm
  Heavy metals ≤10ppm confirm
  PH 4.5-6.5 5.8
  Residue on ignition ≤0.10% 0.05%
  Loss on Drying ≤ 0.5% 0.19%
  Assay 98.0 -101.0% 100.1%
  Conclusion Confirms USP 32
  
  

• CAS Registry Number:

  136-47-0

• Synonyms:

  ;Tetracaine HCl;2-dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride;4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride;4-(butylamino)-Benzoic acid, 2-(dimethylamino)ethyl ester, monohydrochloride;p-butylaminobenzoyl-2-dimethylaminoethanol hydrochloride;Amethocaine hydrochloride;Anethaine;Butethanol;Curtacain;Decicain;Gingicain M;Menonasal;Pantocaine;Pontocaine hydrochloride;Tonexol;Tetracaine·HCL;2-(dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride (1:1);Tertracaine HCL;

• Molecular Formula:

  C₁₅H₂₅ClN₂O₂

• Molecular Weight:

  300.8242

• Molecular Structure:

  

• Hazard Symbols:

   T:Toxic;
  

• Risk Codes:

  R25:;
  R36:;
  R43:;
  

• Safety Description:

  S26:;
  S36/37:;
  S45:;
  

• Company:

  Wuhan Yuancheng Gongchuang Technology Co.Ltd.     [ China ]        

• Contact:

  jorcelyn

• Tel:

  86-027-50756069

• Fax:

• Email:

  ycsales@chembj.com