Bimatoprost

Post Date:
Jun 15,2015
Expiry Date:
Jun 14,2016
Detailed Description:
Cas No. :155206-00-1 Appearance
White or almost white powder
Complies
Identification
(1) by HPLC
Complies
(2) by IR
Complies
Optical rotation
+33.0º to +37.0 º
35.4 º
Water
Not more 1.0%
0.38%
Residual substance
15R-Bimatoprost: N.M.T:0.3%
0
Bimatoprost free acid: N.M.T:0.1%
0
5,6-trans-bimatoprost: N.M.T:0.5%
0
Any single impurity: N.M.T:0.1%
0.06%
Total impurities: N.M.T:0.5%
0.06%
Residual solvents
Acetonitrile: N.M.T:0.04%
0
Ethanol: N.M.T:0.5%
0
n-Hexane: N.M.T:0.05%
0
Ethyl acetate: N.M.T:0.4%
0.02%
Assay
96.0% to 102.0%
99.5%
CAS Registry Number:
155206-00-1
Synonyms:
;N-Ethyl-9Alpha,11Alpha,15S-Trihydroxy-17-Phenyl-18,19,20-Trinor-Prosta-5Z, 13E-Dien-1-Amide;LUMIGAN;Bimatoprost(TM);17-phenyl TRINOR prostaglandin F2ALPHA ethyl amide;Bimatoprost(LUMIGAN);17-phenyl-tri-norprostaglandin f2α-ethyl amide;(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide;(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide;(5E)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}-N-ethylhept-5-enamide;
Molecular Formula:
C₂₅H₃₇NO₄
Molecular Weight:
415.5656
Molecular Structure:

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