Buserelin acetate

Post Date:
Jan 26,2013
Expiry Date:
Jan 26,2014
Detailed Description:
Cas No. :68630-75-1 Quantity: 1mg~Kg
Molecular Formula：
C60H85N15O13

Relative Molecular Mass：
1239.44 g/mol

CAS-Number：
57982-77-1 (net), 68630-75-1 (acetate)

Long-term Storage：
-20 ± 5 °C

Synonym：
(Des-Gly10,D-Ser(tBu)6,Pro-NHEt9)-LHRH

Sequence：
Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt
acetate salt

Fields of Application：
Use in reproduction medicine
Advanced hormone-dependent prostate cancer
Endometriosis
Central precocious puberty
Uterine myoma

Active Substance：
Buserelin is a potent LHRH (GnRH) agonist. After a transient increase, continuous administration of buserelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
CAS Registry Number:
68630-75-1
Synonyms:
Buserelin acetate [USAN:JAN];5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate (salt);Buserelin acetate;HOE 766 MP;HOE 766MP;Luteinizing hormone-releasing factor (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, monoacetate (salt);Receptal;Suprefact;5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide acetate (1:1);
Molecular Formula:
C₆₂H₉₀N₁₆O₁₅
Molecular Weight:
1299.4762
Molecular Structure:

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