CAS 129453-61-8 Cutting Cycle Steroids Anti Estrogen Faslodex Hormonal Fulvestrant

• Post Date:

  Apr 18,2016

• Expiry Date:

  Apr 18,2017

• Detailed Description:

  Cas No. :129453-61-8 Quantity: 5000Kilograms
  Specs:mxy01@ycphar.com
  Price:Negotiable USD Kilograms
  Payment Method: Western Union,Money Gram,T/T,Bitcoin
  CAS 129453-61-8 Cutting Cycle Steroids Anti Estrogen Faslodex Hormonal Fulvestrant
  
  
  Quick Details:
  
  Fulvestrant
  Alias:Faslodex AstraZeneca
  CAS Registry Number:129453-61-8
  Assay: 97.0%~103.0%
  Molecular Fomular:C32H47F5O3S
  Molecular Weight:606.77
  Density:1.201 g/cm3
  Melting Point:104-106℃
  Appearance:white powder
  Grade : Pharmaceutical Grade
  Storage: Shading, confined preservation
  Manufacturer :Hezhong
  Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane
  Usage:Fulvestrant is a type of hormone treatment. It is also called Faslodex. It is a treatment for post menopausal women with advanced breast cancer.A novel steroidal estrogen antagonist reported to lack any partial agonist activity. Also used as an antineoplastic raw materials.
  
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  Application:
  
  Fulvestrant (Faslodex, AstraZeneca) is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works by down-regulating the estrogen receptor.
  
  Fulvestrant is a selective estrogen receptor down-regulator (SERD). Fulvestrant is indicated for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. The dosing schedule for fulvestrant remains under investigation in an attempt to optimize its effectiveness.
  
  Fulvestrant provided effective second-line therapy in this setting for postmenopausal women who had relapsed or progressed after previous endocrine therapy.
  
  In particular 4 clinical trials in this setting did show similar efficacy to the other hormonal agents (aromatase inhibitors and tamoxifen) with good tolerability profile. Fulvestrant had a lower incidence of joint disorders.
  
  Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive. Drugs that block the effects of these hormones can slow or stop the growth of the breast cancer cells. Fulvestrant stops oestrogen getting to the cancer cells by blocking oestrogen receptors and reducing the number of receptors the cancer cell has.
  
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• CAS Registry Number:

  129453-61-8

• Synonyms:

  ;(7a,17b)-7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol;(7alpha,17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol;(17beta)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1,3,5(10)-triene-3,17-diol;Faslodex;

• Molecular Formula:

  C₃₂H₄₇F₅O₃S

• Molecular Weight:

  606.7708

• Molecular Structure:

  

• Company:

  Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.     [ China ]        

• Contact:

  Sukie Liu

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