Clemastine fumarate

• Post Date:

  Mar 08,2021

• Expiry Date:

  Mar 08,2022

• Detailed Description:

  Cas No. :14976-57-9 Specs:White or off-white crystalline powder; 98%
  Clemastine fumarate
  MF： C25H30ClNO5
  MW： 459.96
  CAS： 14976-57-9
  EINECS: 239-055-2
  
  White or off-white crystalline powder;
  
  
  Clarity and color of solution Test solution is colorless or not more intensely colored than Color matching fluid
  
  Melting Point 140~145℃
  
  Identification Infrared AbsorptionTLC
  
  Specific rotation [α]D20 +15°～+18 °(c = 1 in methanol)
  
  PH 3.2～4.2
  
  Loss on drying ≤0.5%
  
  Heavy Metal ≤20ppm
  
  Individual impurity≤ 0.5%
  
  Total Impurities ≤1.0%
  
  Residual solvents 500ppm（Ethanol）
  
  Assay(dried base) 98.0%～102.0%
  
  
  
  Stability data is available.
  
  
  
  
  Second generation H1 receptor antagonists
  
  Antihistamines.
  
  

• CAS Registry Number:

  14976-57-9

• Synonyms:

  ;clemastine hydrogen fumarate;(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine;(2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine (2E)-but-2-enedioate;;CLEMASTINE;CLEMASTINE FUMARATE SALT;CLEMASTINUM;(2R)-2-[2-[(1R)-1-(4-CHLOROPHENYLETHOXY)]ETHYL]-1-METHYL-2-PYRROLIDINE FUMARATE;(+)-(2R)-2-[2-[[(R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine;Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, [R-(R*,R*)]-;Pyrrolidine, 2-2-(1R)-1-(4-chlorophenyl)-1-phenylethoxyethyl-1-methyl-, (2R)-;Pyrrolidine, 2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-, (+)- (8CI);2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine;

• Molecular Formula:

  C₂₁H₂₆ClNO·C₄H₄O₄

• Molecular Weight:

  459.9624

• Molecular Structure:

  

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