Clothianidin

• Post Date:

  Dec 08,2014

• Expiry Date:

  Dec 08,2015

• Detailed Description:

  Cas No. :210880-92-5 Specs:95% TC
  Payment Method: TT LC
  Common name (ISO) Clothianidin
  Chemical name (IUPAC) (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
  Chemical name (CA) [C(E)]-N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitroguanidine
  CAS No 210880-92-5
  Minimum purity min. 960 g/kg (full scale manufacturing)
  Molecular formula C6H8ClN5O2S
  Molecular mass 249.7 g/mol
  Melting point 176.8°C (99.7%)
  Boiling point Not applicable (not a low melting substance)
  Appearance clear and colourless powder, odourless (99.7%)
  dim yellow powder, odourless (97.6%)
  Relative density D420 = 1.61 (99.7%)
  Vapour pressure 3.8 x 10-11 Pa at 20°C
  Solubility in water Milli-Q water : 0.327 g/L at 20°C
  pH 4: 0.304 g/L at 20°C
  pH 10: 0.340 g/L at 20°C
  Solubility in organic solvents solubility at 25°C in
  heptane : < 0.00104 g/L
  xylene : 0.0128 g/L
  dichloromethane : 1.32 g/L
  methanol : 6.26 g/L
  octanol : 0.938 g/L
  acetone : 15.2 g/L
  ethylacetate : 2.03 g/L
  Partition co-efficient (log Pow) pH 4: 0.893 at 25°C
  pH 7: 0.905 at 25°C
  pH 10: 0.873 at 25°C
  Hydrolytic stability (DT50) pH 4 : stable at 50°C
  pH 7 : stable at 50°C
  pH 9 : 1401 d at 20°C
  Dissociation constant pKa = 11.09
  Quantum yield of direct photo-transformation in water at l >290 nm 0.014
  Flammability not highly flammable
  Explosive properties not explosive
  UV/VIS absorption (max.) neutral conditions :
  lmax 265.5 nm : e = 1.71 x 104 L.mol-1.cm-1
  lmax 214.5 nm : e = 7.77 x 103 L.mol-1.cm-1
  at 290 nm : e = 5350 L.mol-1.cm-1
  Photostability in water (DT50) pH 7 : 3.3 hr at 25°C
  
  Ecotoxicology
  Acute toxicity to mammals: LD50 (mice) = 389 mg a.s./kg bw
  Acute toxicity to birds: LD50 (Japanese quail) = 430 mg a.s./kg bw
  Dietary toxicity to birds: LC50 (mallard duck) > 752 mg a.s./kg bw
  Reproductive toxicity to birds: NOEC (bobwhite quail) = 56.8 mg a.s./kg bw
  Short term oral toxicity to mammals: NOAEL (28 d) (mice) = 190 mg a.s./kg bw
  Acute oral toxicity: LD50 = 0.00379 µg a.s./bee
  LD50 = 3.9 µg TZNG/bee
  Acute contact toxicity: LD50 = 0.04426 µg a.s./bee
  
  Acute toxicity
  Rat LD50 oral: 500 mg/kg bw < LD50 < 2000 mg/kg bw
  Rat LD50 dermal: No data
  Rabbit LD50 dermal: >2000 mg/kg b.w./d
  Rat LC50 inhalation: >5.54 mg/l air
  Skin irritation: not irritant
  Eye irritation: not irritant
  
  MAMMALIAN TOXICOLOGY
  Oral Acute oral LD50 for male and female rats >5000 mg/kg. Skin and eye Acute percutaneous LD50 for male and female rats >2000 mg/kg. Slightly irritating to eyes, not a skin irritant (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for male and female rats >6.1 mg/l. NOEL (2 y) for male rats 27.4, female rats 9.7 mg/kg b.w. daily; (1 y) for male dogs 7.8, female dogs 8.5 mg/kg b.w. daily. Other Not mutagenic. Not oncogenic in rats and mice. Not teratogenic in rats and rabbits.
  
  Usage
  Mainly used for rice, vegetables, fruit trees and other crops to combat aphids, leafhoppers, thrips, planthoppers, Hemiptera, Coleoptera, Diptera and certain lepidopteran pests
  
  Mode of action
  Biochemistry Agonist of the nicotinic acetylcholine receptor, affecting the synapses in the insect central nervous system. Translaminar and root systemic activity.
  
  HAZARDS IDENTIFICATION
  Caution: harmful if swallowed or absorbed through skin. Avoid contact with eyes, skin and clothing. Avoid breathing vapors or spray mist. Keep out of reach of children.
  
  Eye: This product is expected to cause minimal or no eye irritation. The expected adverse health effects resulting from an exposure may include redness and possibly some minor swelling..
  
  Skin: This product is minimally toxic when absorbed through the skin. This product can cause brief and/or minor irritation. The expected adverse health effects resulting from an exposure may include redness and possibly some minor swelling. This product is not expected to cause allergic skin reactions. 
  
  Ingestion: This product is slightly toxic when ingested.
  
  Inhalation: This product is minimally toxic when inhaled.

• CAS Registry Number:

  210880-92-5

• Synonyms:

  ;(E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine;1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine;guanidine,N-[(2-chloro-5-thiazoly1)methyl~-N-methyl-N-nitro;3-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-1-nitro-guanidine;(E)-1-(2-Chloro-5-thiazolylmethyl)-3-methyl-2-nitroguanidine;1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine;

• Molecular Formula:

  C₆H₈ClN₅O₂S

• Molecular Weight:

  249.678

• Molecular Structure:

  

• Company:

  Wuhan Agri-Soul Chemical Co.,Ltd.     [ China ]        

• Contact:

  Sophie He

• Tel:

  +86-27-87106715

• Fax:

  +86-27-87397336

• Email:

  sophie.agrisoul@gmail.com