Cyproterone acetate

• Post Date:

  Jan 18,2018

• Expiry Date:

  Jul 17,2018

• Detailed Description:

  Cas No. :427-51-0 Product name: Cyproterone acetate
  Cyproterone acetate CAS register number: 427-51-0
  Cyproterone acetate EINECS: 207-048-3
  Cyproterone acetate Molecular formula: C24H29ClO4
  Cyproterone acetate Molecular weight: 416.94
  Cyproterone acetate Assay: 98%
  Cyproterone acetate Appearance:White crystalline powder
  Cyproterone acetate sometimes abbreviated as CPA, and sold under brand names such as Androcur and Cyprostat, is a synthetic steroidal antiandrogen drug with additional progestogen and antigonadotropic properties. Its primary action is to suppress the activity of the androgen hormones such as testosterone and its more potent metabolite dihydrotestosterone (DHT) in the body, effects which it mediates via competitive antagonism of the androgen receptor and inhibition of enzymes in the androgen biosynthesis pathway. The main therapeutic indications of cyproterone acetate are prostate cancer, benign prostatic hyperplasia, priapism, hypersexuality (e.g., as a form of chemical castration), and other conditions in which androgen action maintains the disease process. In addition, it can also be used to treat acne and hirsutism in females, and is a common component in hormone therapy for transsexual women.
  
  In addition to its antiandrogen properties, cyproterone acetate has weak progestogen activity (i.e., it acts like progesterone). Accordingly, it can be used to treat hot flashes, and is also a component of some combined oral contraceptive pills such as Dianette in the United Kingdom and Diane-35 in other countries such as Canada. It is called Dixi-35 in Chile. No form of cyproterone acetate is available in the United States.
  
  Until the development of leuprorelin, cyproterone acetate was one of the few drugs used to treat precocious puberty. It was also used in animal experimentation to investigate the actions of androgens in fetal sexual differentiation.

• CAS Registry Number:

  427-51-0

• Synonyms:

  ;1,2-alpha-Methylene-6-chloro-(sup 4,6)-pregnadiene-17-alpha-ol-3,20-dione 17-alpha-acetate;1,2-alpha-Methylene-6-chloro-delta(sup 6)-17-alpha-hydroxyprogesterone acetate;1,2-alpha-Methylene-6-chloro-pregna-4,6-diene-3,20-dione 17-alpha-acetate;17-alpha-Acetoxy-6-chloro-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dione;3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 17-(acetyloxy)-6-chloro-1,2-dihydro-, (1beta,2beta)-;6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat;6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat [German];6-Chloro-1,2-alpha-methylene-17-alpha-hydroxy-delta(sup 6)-progesterone acetate;6-Chloro-1,2-alpha-methylene-6-dehydro-17-alpha-hydroxyprogesterone acetate;6-Chloro-17-hydroxy-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dione acetate;6-Chloro-1beta,2beta-dihydro-17-hydroxy-3'H-cyclopropa(1,2)-pregna-1,4,6-triene-3,20-dione acetate;6-Chloro-delta(sup 6)-1,2-alpha-methylene-17-alpha-hydroxyprogesterone acetate;6-Chloro-delta-6-1,2alpha-methylene-17alpha-hydroxyprogesterone acetate;Androcur;CCRIS 4385;Cyprostat;Cyproteron acetate;Cyproteron-R acetate;Cyproterone 17-O-acetate;Cyproterone 17alpha-acetate;HSDB 3592;NSC 81430;NSC-81430;Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1-alpha,2-alpha-methylene-, acetate;SH 714;SH 80714;UNII-4KM2BN5JHF;3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 6-chloro-1-beta,2-beta-dihydro-17-hydroxy-, acetate;6-Chloro-1-beta,2-beta-dihydro-17-hydroxy-3'H-cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione 17-acetate;(1R,7aR,8aS,8bS,10aS)-1-acetyl-5-chloro-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,7,7a,8,8a,8b,8c,9,10,10a-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-1-yl acetate;

• Molecular Formula:

  C₂₄H₂₉ClO₄

• Molecular Weight:

  416.9377

• Molecular Structure:

  

• Hazard Symbols:

   Xn:Harmful;
  

• Risk Codes:

  R20/21/22:;
  R40:;
  

• Safety Description:

  S26:;
  S36:;
  

• Company:

  Wuhan Jiaye Technology Co.,LTD     [ China ]        

• Contact:

  shirley

• Tel:

  15872388127

• Fax:

  86-27-88048077

• Email:

  shirley@ycgmp.com