Dapoxetine / Dapoxetine hydrochloride / CAS 129938-20-1

• Post Date:

  Dec 30,2015

• Expiry Date:

  Dec 29,2016

• Detailed Description:

  Cas No. :129938-20-1 Quantity: 500Kilograms
  Specs:Email:anthony@chembj.com
  Payment Method: Western Union, MoneyGram, T/T
  

  Dapoxetine / Sex Steroid Hormone / CAS 129938-20-1

   

  • Dapoxetine hydrochloride 
  • Other name:Priligy
  • Molecular Formula: C9H7ClN2O5 
  • Molecular weight: 341.88 
  • CAS No: 129938-20-1 
  • Content: 99% 
  • Quality standard: Enterprise standard 
  • Apperance: Light yellow powder, smelless, a little sweet. 
  • Packing: 1kg/foil bag 
  • Storage: Shading, confined preservation 
    Dapoxetine
    Alias: Priligy
    CAS No: 129938-20-1
    MF: C21H23NO. HCl
    MW: 341.88
     
    
     
    Purity: 98%
    Appearance: White powder, odorless, slightly sweet, soluble in water and alcohol.
     

  Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18–64 years old.Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
   
  Treat male premature ejaculation and erectile dysfunction.
  Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger’s meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug’s accumulation in the body, and therefore reducing side effects.

  ————————————————————

  Guangzhou Quanao Chemical Co., Ltd. Is a collection research and development, production, marketing in an integrated modern large-scale chemical pharmaceutical enterprises.Is the national high and new technology enterprise, national biotechnology industrialization leading enterprise, national guard contract, heavy credit enterprise.Main business for the steroid drug substances and drug products development, production and sales.Main production covers an area of 433.49 acres, the existing staff more than 2300 people, including technical staff accounted for 15%, sales staff accounted for 35%, is a comprehensive drug substances and drug products manufacturers.

   

• CAS Registry Number:

  129938-20-1

• Synonyms:

  ;DAPOXETINE HCL;Rimonabant 75000;LY-21044;((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride);(S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride;(1S)-N,N-Dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride;(S)-n,n-dimethyl-3-(naphthalene-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride;N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (1:1);DL-Dapoxteine HCL;Hydrochloric acid Dapoxetine;S-Dapoxetine hydrochloride;D-Dapoxetine HCL;D-Dapoxetine Hydrochloride;

• Molecular Formula:

  C₂₁H₂₄ClNO

• Molecular Weight:

  341.8744

• Molecular Structure:

  

• Company:

  Guangzhou Quanao Chemical Co., Ltd     [ China ]        

• Contact:

  Anthony

• Tel:

  18102817798

• Fax:

  86-020-68886696

• Email:

  anthony@chembj.com