Enfuvirtide Acetate

• Post Date:

  Oct 12,2016

• Expiry Date:

  Apr 10,2017

• Detailed Description:

  Cas No. :159519-65-0 Quantity: 1Kilograms
  Price:1 USD Kilograms
  Payment Method: T/T
  Product Name Enfuvirtide Acetate (T-20)
  Sequence CH3CO-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu
  -Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-
  Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys
  -Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
  Cas No. 159519-65-0
  Molecular Formula C204H301N51O64
  Molecular Weight 4492
  Purity (HPLC) 98.0%min.
  Appearance? White to off-white amorphous solid
  Single Impurity (HPLC)? 0.5%max
  Amino Acid Composition? ±10% of theoretical
  Peptide Content (N%) ≥80.0%
  Water Content (Karl Fischer)? ≤8.0%
  TrifluoroAcetate Content(HPIC) ≤12.0%
  MS (ESI) Consistent
  Mass Balance? 95.0~105.0%
  
  
  2. Description:
  
  Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS. It binds to the first heptad-repeat (HR1) in the gp41 subunit of the viral envelope glycoprotein and prevents the conformational changes required for the fusion of viral and cellular membranes. It works by disrupting the HIV-1 molecular machinery at the final stage of fusion with the target cell, preventing uninfected cells from becoming infected.
  
  3. Application:
  
  Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection. It is marketed under the trade name Fuzeon (Roche).

• CAS Registry Number:

  159519-65-0

• Synonyms:

  ;T-2;Enfuvirtide(T-20);Enfurvitide(T-20);Pentafuside;Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH{2};1-{[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-(butan-2-yl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}prolyl-N~5~-(diaminomethylidene)ornithylglycinamide;Enfuvirtide Acetate;

• Molecular Formula:

  C₂₀₄H₃₀₁N₅₁O₆₄

• Molecular Weight:

  4491.87603999998

• Molecular Structure:

  

• Company:

  Hubei Yuancheng Saichuang Technology Co.,Ltd.     [ China ]        

• Contact:

  fion

• Tel:

  +86-027-50755967

• Fax:

• Email:

  wq2014@yccreate.com