Epalrestat

Post Date:
Nov 15,2013
Expiry Date:
Nov 15,2014
Detailed Description:
Cas No. :82159-09-9 Epalrestat
CAS No. 82159-09-9
M. F. C15H13NO3S2
Molecular Weight: 319.401

Epalrestat inhibits Aldose Reductase (AR) involved in the rate limiting step in the conversion of glucose to sorbitol under hyperglycemic conditions. Aldose reductase has been the target of multiple clinical investigatons to treat diabetic neuropathy and retinopathy. Epalrestat is an approved drug in Japan and India, used for the treatment of diabetic neuropathy.

ABATRA TECHNOLOGY CO., LTD
s k y p e: abatra50
Room 203, Mei Ou Building, No. 4 Gaoxin-2 Road, Hi-Tech Development Zone, Xi'an, 710075, China
CAS Registry Number:
82159-09-9
Synonyms:
;Epalrestat [INN];Ono 2235;5-((1Z,2E)-2-Methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestatum;Epalrestatum [Latin];UNII-424DV0807X;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;{(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid;{(5E)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid;Kinedak;
Molecular Formula:
C₁₅H₁₃NO₃S₂
Molecular Weight:
319.3986
Molecular Structure:

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