Exemestane

• Post Date:

  Oct 20,2015

• Expiry Date:

  Oct 19,2016

• Detailed Description:

  Cas No. :107868-30-4 Quantity: 1000Kilograms
  Specs:ISO
  Price:1 USD Kilograms
  Payment Method: western union moneygram T/T bank transfer
  

  Exemestane

  China Best Selling Aromasin Raw Materials Exemestane Acatate  Antiestrogen
  Product Category: Pharmaceutical raw materials and intermediates
  Appearance: White or Almost White Crystalline Powder
  Product content: ≥ 99%
  CAS:107868-30-4
  Molecular formula: C20H24O2
  Molecular Weight:296.40
  hnzz01 at  ycgmp  dot  com

  Sky pe:(live:hanhan9937)

  Packing specifications: 25kg / barrel
  Usage:antiinfective

  Sky pe:(live:hanhan9937)
  Product Details:Place of Origin: China
  Brand Name: Yuancheng
  Certification: agnes-pharmade
  Payment & Shipping Terms:Minimum Order Quantity: 100ml
  Price: Negotiable
  Packaging Details: Foil bag or as requirement
  Delivery Time: 24 hours after payment
  Payment Terms: Western Union, MoneyGram, Bank Transfer
  Supply Ability: 2000ml/month

  
  Product Description

  Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.

  The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.

  Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.

  The estrogen suppression rate for exemestane varies from 35% for estradiol (E2) to 70% for estrone (E1).

   

  • We specialized in pharmaceutical chemicals' production for over 10 years,
  • very rich experience in custom,we have professinal packing team,and fastest delivery time,
  • packing pictures and tracking codes will be sent to you within 48 hours after your order.
  • have reshipping policy to many countries.

  hnzz01 at  ycgmp  dot  com
  Sky pe:(live:hanhan9937)

• CAS Registry Number:

  107868-30-4

• Synonyms:

  ;Exemestan;6-Methylenandrosta-1,4-diene-3,17-dione;10,13-Dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-;6-methylideneandrosta-1,4-diene-3,17-dione;(8ξ,9ξ,14ξ)-6-methylideneandrosta-1,4-diene-3,17-dione;Exemestane(Aromasin);Exemestone;

• Molecular Formula:

  C₂₀H₂₄O₂

• Molecular Weight:

  296.4034

• Molecular Structure:

  

• Company:

  Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd     [ China ]        

• Contact:

  hanhan

• Tel:

  8618188931013

• Fax:

  8618188931013

• Email:

  hanhan11@chembj.com