Fludarabine phosphate

• Post Date:

  Apr 14,2014

• Expiry Date:

  Apr 14,2015

• Detailed Description:

  Cas No. :75607-67-9
  Name Fludarabine phosphate
  Molecular Formula C10H13FN5O7P
  Molecular Weight 365.21
  CAS Registry Number 75607-67-9
  
  White to off-white crystalline hygroscopic powder; soluble in acid, alkali and slightly in water
  Specific of rotation: +10°～+14°(in 5mg/ml of water)
  Water ≤3.0%
  Heavy metals ≤0.002%
  Free phosphate ≤0.1%
  Sodium ≤0.2%
  Chloride ≤0.2%
  Total microbial count: ≤1000CFU/g
  Fludarabine bisphosphate (3,5-diphosphate analog): ≤0.4%
  Isoguanine: ≤0.2%
  Iso-ara-guanine monophosphate: ≤0.8%
  2-ethoxyphosphate analog: ≤0.2%
  2-Fluoro-ara-adcnine: ≤0.2%
  2-fluoroadenine: ≤0.1%
  Impurity A: ≤0.1%
  Impurity B: ≤0.1%
  Other biggest impurity: ≤0.5%
  Total impurity: ≤1.5%
  Methanol: ≤2000ppm
  Ethanol: ≤3000ppm
  Dichloromethane: ≤600ppm
  Assay (HPLC) 98.0～102.0%
  
  For B-cell chronic lymphocytic leukemia (CLL) patients treated.

• CAS Registry Number:

  75607-67-9

• Synonyms:

  ;Fludarabin Phosphate;9-bata-D-Arabinofuranosyl-2-fluoroadenine phosphate;9-b-D-Arabinofuranosyl-2-fluoroadenine-5-(dihydrogen phosphate);2-fluoro-9-(5-O-phosphonopentofuranosyl)-9H-purin-6-amine;2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine;9-beta-arabinofuranosyl-2-fluoroadenine-5'-phosphate;2-Fluoro-9-(5-O-phosphono-β-D-arabinofuranosyl)-9H-purin-6-amine;9-β-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate;

• Molecular Formula:

  C₁₀H₁₃FN₅O₇P

• Molecular Weight:

  365.2117

• Molecular Structure:

  

• Company:

  kinfon pharmachem co.,ltd     [ China ]        

• Contact:

  kfpharma

• Tel:

  0086238650081

• Fax:

  0086238650081

• Email:

  info@kfpharmachem.com