Genz-123346
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Post Date:
Apr 03,2015
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Expiry Date:
Apr 02,2016
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Detailed Description:
Cas No. :491833-30-8
Quantity: 50g
Specs:98% purity
Payment Method: T/T, Western Union
Genz-123346 is a glucosylceramide synthase inhibitor with potential anticancer
activity. Exposure of cells to Genz-123346 and to other GCS inhibitors at non-toxic concentrations can enhance the killing of tumor cells by cytotoxic anti-cancer agents. Genz-123346 and a few other GCS inhibitors are substrates for multi-drug resistance efflux pumps such as P-gp (ABCB1, gP-170). In cell lines selected to over-express P-gp or which endogenously express P-gp, chemosensitization by Genz-123346 was primarily due to the effects on P-gp function.
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CAS Registry Number:
491833-30-8
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Company:
Shanghai Sun-shineChemical Technology Co.,Ltd.
[ China ]
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Contact:
Rosie
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Tel:
+86-027-59253327
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Fax:
0086-27-5925 3326
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Email:
sales02@sun-shinechem.com
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