Goserelin acetate

• Post Date:

  Dec 17,2018

• Expiry Date:

  Dec 17,2019

• Detailed Description:

  Cas No. :145781-92-6 Goserelin acetate
  Growth Hormone Peptides Goserelin Acetate For Bodybuilding
  Basic info:Goserelin Acetate
  Sequence: Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Aza-Gly-NH2
  Cas No.: 145781-92-6
  Molecular Formula: C61H88N18O16
  Molecular Weight: 1269.4
  Purity (HPLC): 98.0%min.
  Appearance: White powder
  Single Impurity (HPLC): 0.5%max
  Amino Acid Composition: ±10% of theoretical
  Peptide Content (N%): ≥80.0%
  Water Content(Karl Fischer): ≤8.0%
  Acetate Content(HPIC): ≤10.0%
  MS (ESI): Consistent
  Mass Balance: 95.0~105.0%
  Product Information:
  1. Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.
  2. GnRH is available as gonadorelin hydrochloride )and gonadorelin diacetate tetrahydrate for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
  3. Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens.
  The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.
  

• CAS Registry Number:

  145781-92-6

• Synonyms:

  PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA)GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-LUTEINIZING HORMONE-RELEASING HORMONE;GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2;(D-SER(TBU)6,AZAGLY10)-LHRH;(D-Ser(tBu)6,Azagly10)-LHRH acetate salt;Goserelin HCl;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER(T-BU)-LEU-ARG-PRO-AZAGLY-NH2];5-oxoprolylhistidyl-N-[18,18-diamino-7-(tert-butoxymethyl)-13-({2-[(2-carbamoylhydrazinyl)carbonyl]pyrrolidin-1-yl}carbonyl)-4-(4-hydroxybenzyl)-1-(hydroxymethyl)-10-(2-methylpropyl)-2,5,8,11-tetraoxo-3,6,9,12,17-pentaazaoctadec-17-en-1-yl]tryptophanamide acetate (1:1);(2S)-N-[(2S,5S,8S,11S,14R,17S,20S)-25-amino-14-(tert-butoxymethyl)-20-({(2S)-2-[(2-carbamoylhydrazinyl)carbonyl]pyrrolidin-1-yl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-4-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-(2-methylpropyl)-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxopyrrolidine-2-carboxamide acetate (1:1) (non-preferred name);D-Ser(tBu)6,AzaGly10)-LHRH acetate salt;

• Molecular Formula:

  C₆₁H₈₈N₁₈O₁₆

• Molecular Weight:

  1329.4624

• Molecular Structure:

  

• Safety Description:

  S22-24/25:;
  

• Company:

  Koffee Pharm Co., Ltd     [ China ]        

• Contact:

  Sophia

• Tel:

  +86-21-61729394

• Fax:

  +86-21-61729394

• Email:

  sophia.koffeepharm@gmail.com