Ketoconazole

• Post Date:

  Sep 10,2014

• Expiry Date:

  Mar 09,2015

• Detailed Description:

  Cas No. :65277-42-1 Quantity: 25Kilograms
  Name Ketoconazole
  Synonyms cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine
  Product Name: Ketoconazole
  Synonyms: ,3-dioxolan-4-yl)methoxy)phenyl)-,cis-;fungarest;fungoral;ketoconazol;ketoderm;ketoisdin;kw-1414;nizoral
  CAS: 65277-42-1
  MF: C26H28Cl2N4O4
  MW: 531.43
  EINECS: 265-667-4
  Product Categories: Active Pharmaceutical Ingredients;Organics;Antifungals for Research and Experimental Use;Antitumors for Research and Experimental Use;Biochemistry;Antibiotic Explorer;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;API's;Antifungal;Heterocycles;Isotopically Labeled Pharmaceutical Reference Standard;KETOZOLE
  Mol File: 65277-42-1.mol
  Ketoconazole Chemical Properties
  mp 146°C
  refractive index -10.5 ° (C=0.4, CHCl3)
  storage temp. 2-8°C
  color white to light yellow
  Merck 5302
  CAS DataBase Reference 65277-42-1(CAS DataBase Reference)
  Safety Information
  Hazard Codes T
  Risk Statements 25-36/37/38-23/24/25
  Safety Statements 36-45-36/37/39-26
  RIDADR UN 2811 6.1/PG 3
  WGK Germany 3
  RTECS TK7912300
  HazardClass 6.1(b)
  PackingGroup III
  Hazardous Substances Data 65277-42-1(Hazardous Substances Data)
  MSDS Information
  Provider Language
  cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine English
  SigmaAldrich English
  Ketoconazole Usage And Synthesis
  Chemical Properties White Powder
  Usage Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor
  Usage antifungal, PXR/SRC1 & CAR/SRC1 inhibitor
  Biological Activity Antifungal agent; potent inhibitor of cytochrome P450c17.
  Ketoconazole Preparation Products And Raw materials
  Raw materials Bromine-->Triethylamine-->Sodium hydride -->Imidazole-->2,2'-Iminodiethanol-->p-Toluenesulfonamide -->2,4 DICHLORO BENZENE
  Preparation Products Itraconazole

• CAS Registry Number:

  65277-42-1

• Synonyms:

  ;cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine;1-[4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone;1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone;1-[4-(4-{[(2S,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone;1-acetyl-4-(4-{[(2R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine;

• Molecular Formula:

  C₂₆H₂₈Cl₂N₄O₄

• Molecular Weight:

  531.4309

• Molecular Structure:

  

• Hazard Symbols:

   T:Toxic;
  

• Risk Codes:

  R25:;
  

• Safety Description:

  S36:;
  S45:;
  

• Company:

  Hubei MaxSource Chem Co., Ltd.     [ China ]        

• Contact:

  jackie xiao

• Tel:

  +86-27-83555670

• Fax:

• Email:

  maxsource14@hotmail.com