Lamivudine

Post Date:
May 24,2013
Expiry Date:
May 24,2014
Detailed Description:
Cas No. :134678-17-4 Lamivudine
Type: APIs, pharmaceutical chemicals, anti virus agent.
Assay: 98.0%~102.0%
Description: White crystalline powder.
Package: 1kg foil bag; 25kg cardboard drum
CAS NO.: 134678-17-4
MF: C8H11N3O3S
MW: 229.26
Usage: A reverse transcriptase inhibitor.
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Function and Usage: Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.
CAS Registry Number:
134678-17-4
Synonyms:
;2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-cis)-;(-) 2'-Deoxy-3'-thiacytidine;2'-Deoxy-3'-thiacytidine;(2R-cis)-4-amino-1-;3'-thia-2',3'-dideoxcytidine;(-)-BCH-189;Epivir;GR109714X;(-)NGPB-21;(2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone;(-)-2￠-deoxy-3￠-thiacytidine;(-)-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cystosine;3￠-thia-2￠,3￠-dideoxycytidine;3TC;4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one;4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one;
Molecular Formula:
C₈H₁₁N₃O₃S
Molecular Weight:
229.2562
Molecular Structure:

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