Linezolid

• Post Date:

  Dec 07,2018

• Expiry Date:

  Dec 07,2019

• Detailed Description:

  Cas No. :165800-03-3 The main use of linezolid is the treatment of severe infections caused by Gram-positive bacteria that are resistant to other antibiotics; it should not be used against bacteria that are sensitive to drugs with a narrower spectrum of activity, such as penicillins and cephalosporins. In both the popular press and the scientific literature, linezolid has been called a "reserve antibiotic"—one that should be used sparingly so that it will remain effective as a drug of last resort against potentially intractable infections.[14][15]
  In the United States, the indications for linezolid use approved by the U.S. Food and Drug Administration (FDA) are the treatment of vancomycin-resistant Enterococcus faecium infections, with or without bacterial invasion of the bloodstream; nosocomial pneumonia (hospital-acquired) and community-acquired pneumonia caused by S. aureus or S. pneumoniae; complicated skin and skin structure infections (cSSSI) caused by susceptible bacteria, including diabetic foot infection, unless complicated by osteomyelitis (infection of the bone and bone marrow); and uncomplicated skin and soft tissue infections caused by S. pyogenes or S. aureus.[3] The manufacturer advises against the use of linezolid for community-acquired pneumonia or uncomplicated skin and soft tissue infections caused by MRSA.[3] In the United Kingdom, pneumonia and cSSSIs are the only indications noted in the product labeling.[16]
  Linezolid appears to be as safe and effective for use in children and newborns as it is in adults.[17]

• CAS Registry Number:

  165800-03-3

• Synonyms:

  ;(s)-n-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide;N-({(5R)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide;N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide;(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide;

• Molecular Formula:

  C₁₆H₂₀FN₃O₄

• Molecular Weight:

  337.3461

• Molecular Structure:

  

• Company:

  Jinan Chenghishaungda Chemical Co.,LTD     [ China ]        

• Contact:

  Allen

• Tel:

  15689693073

• Fax:

  0531-58897032

• Email:

  3118607598@qq.com