Local Anesthetic Lidocaine

• Post Date:

  Sep 30,2017

• Expiry Date:

  Sep 30,2018

• Detailed Description:

  Cas No. :137-58-6 Quantity: 500Kilograms
  Payment Method: west union money gram T/T
  Local Anesthetic Lidocaine
  Lidocaine
  Lidocaine Basic Information:
  Product Name: Lidocaine
  Lidocaine CAS: 137-58-6
  Lidocaine MF: C14H22N2O
  Lidocaine MW: 234.34
  Lidocaine EINECS: 205-302-8
  Lidocaine mp: 66-69°C
  Lidocaine storage temp: Store at RT
  Lidocaine solubility ethanol: 4 mg/mL
  Lidocaine form: powder
  Lidocaine Water Solubility: practically insoluble
  Lidocaine Stability: Stable. Incompatible with strong oxidizing agents.
  Lidocaine Usage: Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
  Lidocaine Description:
  The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action. Epinephrine (adrenaline) vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful.Lidocaine drops can be used on the eyes for short ophthalmic procedures.
  There is tentative evidence for topical lidocaine for neuropathic pain.Intravenous lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two-thirds.
  Lidocaine Application:
  Lidocaine crosses the blood-brain and placental barriers, presumably by passive diffusion.
  Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine. Approximately 90% of Lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged.
  
  99.8% Pain Killer Powder Lidocaine Hydrochloride / Lidocaine HCL Local Anesthetic
  What is the Lidocaine Hydrochloride ?
  Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration
  of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. lidocaine, on the other hand, has the advantage of a rapid onset of action.
  It can stop Epinephrine vasoconstricts arteries form bleeding, and it can also delays the resorption of
  lidocaine, almost doubling the duration of anaesthesia.
  Lidocaine HCl Quick detail :
  Product name:Lidocaine HCl
  Lidocaine HCl Other name:Lidocaine hydrochloride
  Lidocaine HCl CAS register number:73-78-9
  Lidocaine HCl EINECS:200-803-8
  Lidocaine HCl Molecular formula:C14H23ClN2O
  Lidocaine HCl Molecular weight:270.8
  Lidocaine HCl Pure 73-78-9
  

• CAS Registry Number:

  137-58-6

• Synonyms:

  ;2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide;Lignocaine;2-diethylaminoacet-2,6-xylidide;Xylocaine;N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide;2-[(2,6-dimethylphenyl)amino]-N,N-diethyl-2-oxoethanaminium;Lidocaine base;

• Molecular Formula:

  C₁₄H₂₃N₂O

• Molecular Weight:

  235.3447

• Molecular Structure:

  

• Hazard Symbols:

   Xn:Harmful;
  

• Risk Codes:

  R22:;
  

• Safety Description:

  S22:;
  S26:;
  S36:;
  

• Company:

  hubei gongchuang ltd.c     [ China ]        

• Contact:

  ulalee

• Tel:

  +86-571-15784251

• Fax:

• Email:

  gcgj11@ycphar.com