Loperamide hydrochloride

• Post Date:

  Mar 24,2014

• Expiry Date:

  Mar 24,2015

• Detailed Description:

  Cas No. :34552-83-5 Quantity: 50000Kilograms
  Loperamide hydrochloride
  Synonyms: Lopemin; Loperamide HCl
  CAS: 34552-83-5
  EINECS: 252-082-4
  Assay: 99% min.
  Standard: BP/EP/USP
  Packing: 1kg/foil bag; 5kg/drum.
  Character: White Solid.
  Usage: used as an antidiarrheal, treatment of diarrhea.
  Biological Activity: High affinity μ -opioid receptor agonist with peripheral selectivity (K i values are 2, 48 and 1156 nM for μ -, δ - and κ -opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca 2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca 2+ channels and at higher concentrations it reduces Ca 2+ flux through NMDA receptor operated channels.
  Gastrointestinal Agents:
  Omeprazole
  Ufiprazole
  Pantoprazole Sodium
  Pantoprazole intermediate
  Esomeprazole Sodium
  Esomeprazole Magnesium
  Ursodeoxycholic acid
  Ricobendazole
  Loperamide HCl

• CAS Registry Number:

  34552-83-5

• Synonyms:

  ;4-(4-(p-Chlorophenyl)-4-hydroxy-1-piperidyl)-N,N-dimethyl-2,2-diphenylbutyramide HCl;4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide HCl;4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride;BLOX;BREK;Dissenten;Fortasec;Imodium;Imodium A-D;Imodium A-D EZ chews;Imosec;Lopemid;Lopemin;Loperamide HCl;Loperyl;Maalox Antidiarrheal;PJ185;R 18553;Suprasec;Tebloc;UNII-77TI35393C;Up and up anti diarrheal;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, hydrochloride;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, monohydrochloride;4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride;4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride (1:1);

• Molecular Formula:

  C₂₉H₃₄Cl₂N₂O₂

• Molecular Weight:

  513.4985

• Molecular Structure:

  

• Hazard Symbols:

   T:Toxic;
  

• Risk Codes:

  R25:;
  

• Safety Description:

  S45:;
  

• Company:

  Hubei Yuancheng Pharmaceutical Co.,Ltd     [ China ]        

• Contact:

  Jane Dong

• Tel:

  +86-27-68886737

• Fax:

  +86-27-88048077-995

• Email:

  ycgsales01@yccreate.com