Losartan Potassium CAS NO: 124750-99-8
-
Post Date:
May 04,2025
-
Expiry Date:
Oct 31,2025
-
Detailed Description:
Cas No. :124750-99-8
Payment Method: LC/TT
Losartan Potassium:
CAS NO: 124750-99-8
Standard: Enterprise Standard
Package: 25kg/barrel
Molecular Formula: C22H22ClKN6O
Molecular Weight: 461.01
Description:
Application:
Assay: ‰¥98.0%
Description:
Losartan is a specific antagonist of the angiotensin II receptor type AT1; it does not inhibit ACE (kininase II), the enzyme that degrades bradykinin. Removal of angiotensin II negative feed back on renin secretion leads to increased plasma renin activity, during losartan administration. A 2 to 3-fold increase in angiotensin II in plasma comes as a result of increases in plasma renin activity. However, antihypertensive activity and suppression of plasma aldosterone concentration are apparent, indicating effective angiotensin II receptor blockade. After discontinuation of losartan, plasma renin activity and angiotensin levels declined.
Specification:
Test Items Standard Result
Description A white or off- white powder white powder
Identification IR,UV,test for potassium Conforms
Water ≤0.5% 0.3%
Any impurity ≤0.2% 0.07%
Total impurity ≤0.5% 0.10%
Heavy metals ≤10ppm ＜10ppm
Assay 98.5%-101.0% 99.9%
Residual solvents
cyclohexane ≤1000ppm 92ppm
Isopropyl alcohol ≤2000ppm 321ppm
Conclusion The results conform with USP29 standard
Our Advantages
1,High quality with competitive price:
1)Standard:EP
2)All Purity≥99%
3)We are manufacturer and can provide high quality products with factory price.
2,Fast and safe delivery
1)Parcel can be sent out in 24 hours after payment.
2)Secure and discreet shipment.Various transportation methods for your choice.
3)Effective after-sale service
4)Tracking your order at any time. Inform your order's further new situation at any time.
-
CAS Registry Number:
124750-99-8
-
Synonyms:
;potassium 5-(4'-{[2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl]methyl}biphenyl-2-yl)tetrazol-1-ide;potassium (2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolate;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol monopotassium salt;
-
Molecular Formula:
C22H22ClKN6O
-
Molecular Weight:
461.001
-
Molecular Structure:
Inquiry