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Methyl p-chlorocinnamate

  • Post Date:

    Dec 18,2019
  • Expiry Date:

    Dec 17,2020
  • Detailed Description:

    Cas No. :7560-44-3 CAS No: 7560-44-3
    Molecular formula: C10H9ClO2
    Molecular weight: 196.5
    Melting point: 78-81℃
    Packing: 25kg Paper barrel
    Assay: ≥99%
    Quality: Enterprise standard
    Physicochemical property: White Crystalline Powder, it can disolve in ethyl alcohol and diethyl ether, can't disolve in water.
    Preparation method: Obtained by reacting chlorocinnamic acid with methanol in the presence of concentrated sulfuric acid.
    Application: This product is an organic synthesis intermediate.
    Storage condition: Seal in a cool, dry environment.
    Stability: If used and stored according to specifications, it will not decompose.

    Methyl p-chlorocinnamate is an organic chemical, often used in industry, pharmaceutical industry, etc., obtained by reacting chlorobenzaldehyde with acetic anhydride. The chlorobenzene formaldehyde, acetic anhydride and sodium acetate with reaction 13 h under 180 ℃. After the reaction, it is slightly cold. Pour into the water, filter and wash the filter cake with water. Dissolve the cake repeatedly with ammonia until only a small amount of brownish-yellow sticky remains remain. The ammonium salt solution was filtered, then the chlorocinnamic acid was precipitated out with 3N dilute sulfuric acid, and the product was filtered and dried.

    Methyl p-chlorocinnamate is mainly used to synthesize methyl bromomethyl cinnamate from the upstream raw material of the antithrombotic agent ozagrel sodium. The methyl methylanilate was prepared by N- butyl diimide bromide bromide and the total yield was 67%.

    Keywords: Methyl p-chlorocinnamate, p-chlorocinnamic acid, 1615-02-7, cinnamic acid
  • CAS Registry Number:

    7560-44-3
  • Synonyms:

    ;4-Chlorocinnamic acid methyl ester;methyl 3-(4-chlorophenyl)prop-2-enoate;methyl (2E)-3-(4-chlorophenyl)prop-2-enoate;
  • Molecular Formula:

    C10H9ClO2
  • Molecular Weight:

    196.6303
  • Molecular Structure:

    7560-44-3 Methyl 4-chlorocinnamate
  • Safety Description:

    S22:Do not inhale dust.;
    S24/25:Avoid contact with skin and eyes.;
  • Company:

    Wuhan LANDMARK Industrial Co., Ltd     [ China ]        
  • Contact:

    Halsey
  • Tel:

    18062529653
  • Fax:

  • Email:

    Halsey.lmd@gmail.com
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