Nervonic acid, CAS:506-37-6
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Post Date:
Nov 01,2016
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Expiry Date:
Nov 01,2017
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Detailed Description:
Cas No. :506-37-6
Quantity: 500Kilograms
Payment Method: TT .L/C
Nervonic acid
Detailed Information:
Key words: Nervonic acid, CAS:506-37-6
Name cis-15-Tetracosenoic acid
Selacholeic acid CAS No 506-37-6
Synonym Nervonic acid Molecular weight 366.62
Molecular formular C24H46O2 Purity 92.00%min
EINECS No / Place of origin china
Application Nutrient，Active ingredient of health care products Appearance white powder
Packing 1Kg/bag,25Kg/drum,or according to the customer request MP 42-46℃
Documents available COA , MSDS ,NMR,HPLC Certificate SGS
MDL Number MFCD00010507
storage Keep in RT, avoid moisture.
Description:
Nervonic acid is an essential nutrient for the growth and maintenance of the brain.
Nervonic acid has been found in breast-milk,it is said it can speed the development in infants. It is the reason why it is recommended to pregnant and nursing women.
Product
Product name Nervonic acid
Synonyms cis-15-Tetracosenoic acid; Selacholeic acid
CAS No. 506-37-6
Molecular formula C24H46O2
Molecular weight 366.62
Appearance white powder
Melting point 42-43 ºC
Assay 92.28%
Packing 1kg/bag or bottle,25kg/drum or packed on the clients' requirements
Application Nutrient，Active ingredient of health care products
Testing Results
Test/Observation Specifications Result
Assay Content % by HPLC 92% 92.28%
Appearance White Crystalline Powder Complies
Odor Characteristic Complies
PH 5.0-7.0 6.09
Clarity of water solution Transparent, colorless, none suspended matters Complies
Loss on drying % MAX 0.5 0.25
Ash % MAX.0.5 0.38
Melting point +202.0-212.0°C Complies
Specific rotation +174.0-+186.0 +181.0
Hydroquinone Negative Complies
Heavy metals PPM MAX.10 Complies
As
Pb
Cd <2ppm
<1ppm
<1ppm Complies
Complies
Complies
Microbiology
Total Plate Count
Yeast & Mold
E.Coli
S. Aureus
Salmonella
<1000cfu/g
<100cfu/g
Negative
Negative
Negative
122 cfu/g
13 cfu/g
Complies
Complies
Complies
Application:
1.Nervonic acid can regulate the function of brain cell membranes and have a neuroprotective effect which is important to high-level training adults or athletes: it is an energy supplement.
2.Due to its function as an intermediate in myelin biosynthesis, dietary therapy with nervonic acid-containing fats has been studied: nervonic acid appears to be beneficial for the treatment of genetic disorders of the lipid metabolism, such as Zellweger syndrome or adrenoleukodistrophy. Nervonic acid beta-oxidation takes place in peroxisomes, and this oxidation is impaired in X-ALD patients.
3.Due to different mutations, people having these disorders have ineffective peroxisomes. It causes an important accumulation of very long chain fatty acids, that can be treated with oils enriched with 24:1 (Lorenzo's oil, Lunaria's oil).
4.Nervonic acid is a regulator of the Ca2+ ion channel in the cell membrane of nerve tissues, so nervonic acid plays an important role in the control of the levels of calcium of the cytosol.
5.Patients with multiple sclerosis have decreased levels of nervonic acid in the brain. An impairment in the provision of nervonic acid in demyelinating diseases (like multiple sclerosis) suggest that a diet rich in very long chain monenoic acid fatty acids, nervonic acid is one of them, may be beneficial.
6.It is also used as a biomarker to predict who will suffer some psychoses. For instance, there is evidence of abnormal levels of fatty acids in individuals with schizophrenia. In particular, decreased levels of 24:1 are related with prodomal psychosis symptoms so it can be beneficial in the prevention and treatment of this kind of disorders.
7.Nervonic acid can be an indicator of future neurodevelopmental disorders in male babies whose mother has preeclampsia. Recent studies show that cord nervonic acid levels were lower in women with preeclampsia delivering male babies as compared to normotensive control group. But this does not happen with girl babies. These results suggest that male babies born to mothers with preeclampsia may be at an increased risk of developing neurodevelopmental disorders as compared to female babies.
8.This acid is present in the composition of aged eye lens, but it does not appear in normal eye lens. This data shows that we can use the presence of nervonic acid (together with heneicosylic acid and docosahexaenoic acid) as biomarkers of aging lens, which is the most vulnerable stage for cataract development.
Contact :
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CAS Registry Number:
506-37-6
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Synonyms:
;cis-15-Tetracosenoic acid;cis-15-Teracosenoic acid;(15Z)-tetracos-15-enoic acid;
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Molecular Formula:
C24H46O2
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Molecular Weight:
366.6208
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Molecular Structure:
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Hazard Symbols:
Xi:Irritant;
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Risk Codes:
R36/37/38:;
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Safety Description:
S26:;
S36:;
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Company:
shenzhen Dieckmann Technology Co.,Ltd
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Contact:
Nancy
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Tel:
0086-13423881513
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Fax:
86-755-84813563
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Email:
sale@dkmchem.com
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