Nootropics Supplement Raw Powder Prl-8-53 for Memory Improvement

• Post Date:

  Sep 30,2017

• Expiry Date:

  Sep 30,2018

• Detailed Description:

  details.:ulalee@yuanchengtech.com
  ,whatsapp: +8618872220744
  Nootropics Raw Powder Prl-8-53 Improve Memory CAS 51352-87-5
  Prl-8-53 HCl CAS51352-87-5 Nootropic Powder for Memory Improving
  
  PRL-8-53 HCL CAS51352-87-5 Nootropic Powder for Memory Improving
  PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.
  Product name PRL-8-53 HCL
  Other name PRL-8053;PRL-8-53 hydrochloride;3-(2-(benzyl(methyl)amino)ethyl)benzoate.
  PRL-8-53 CAS No. 51352-87-5
  PRL-8-53 Molecular formula C18H22ClNO2
  PRL-8-53 Molecular weight 319.82578
  PRL-8-53 Appearance Off white solid powder
  Purity 99%+
  PRL-8-53 Packing 50G or as your requirement
  
  What is PRL-8-53?
  PRL-8-53 is a hypermnesiac nootropic,a synthetic supplement with potential benefits for short term memory. A single study in humans was reported in 1978. The double-blind trial of PRL-8-53 in 47 healthy volunteers measured its effects on a variety of cognitive measures. 5 mg of the drug was administered orally 2-2.5 hours before the study tasks.[1] Overall improvements in recollection differed based on how many words were recalled under placebo, with the poor performers (six words or fewer) experiencing a 87.5-105% increase in recollection and the high performers (eight or more words) a 7.9-14% increase which failed to reach statistical significance; when controlling for subjects over the age of 30 only, a 108-152% increase was noted No side effects were reported during the trial.
  
  PRL-8-53 effects:
  Improves short term memory in all individuals
  Statistically significant increase in working memory for individuals with poor short term memory
  No side effects noted in human trial
  
  PRL-8-53 dosage:
  PRL 8-53 suggests a range of 0.01-4mg/kg of body weight however, as that is a very large range, the ideal range is 0.05-1.2 mg/kg.
  
  HOW IT WORKS
  PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.
  
  Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.

• Company:

  hubei gongchuang ltd.c     [ China ]        

• Contact:

  ulalee

• Tel:

  +86-571-15784251

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