Pazopanib

Post Date:
Dec 27,2016
Expiry Date:
Dec 27,2017
Detailed Description:
Cas No. :444731-52-6 Quantity: 500Kilograms
Specs:99.0%
Payment Method: TT/LC

Product Name: Pazopanib
CAS NO.: 444731-52-6
Synonyms: 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;GW 786034;Benzenesulfonamide,5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-;Votrient;
Molecular Formula: C21H23N7O2S Molecular Weight: 437.52

Specification
Appearance White or off white crystal powder
Assay >99.0%
Boiling Point 728.814 °C at 760 mmHg
Flash Point 394.572 °C

Application: Pazopanib, with its trade name of Votrient, is one kind of potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit that blocks tumor growth and inhibits angiogenesis. For being one oral angiogenesis inhibitor targeting VEGFR and PDGFR, Pazopanib has been approved for renal cell carcinoma and soft tissue sarcoma. What's more, Pazopanib may also be active in ovarian cancer, and pazopanib also appears effective in the treatment of non-small cell lung carcinoma.
Package: Aluminum bag
Storage: Room temperature

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CAS Registry Number:
444731-52-6
Synonyms:
;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide;5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide hydrochloride (1:1);
Molecular Formula:
C₂₁H₂₄ClN₇O₂S
Molecular Weight:
473.979
Molecular Structure: