Pirfenidone

• Post Date:

  Jun 29,2019

• Expiry Date:

  Jun 28,2020

• Detailed Description:

  Cas No. :53179-13-8 Quantity: 10Kilograms
  Price:10 USD Kilograms
  Payment Method: Western Union, Money Gram, Bank Transfer, Bit
  In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
  
  
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• CAS Registry Number:

  53179-13-8

• Synonyms:

  ;5-Methyl-1-phenyl-2-(1H)-pyridone;5-methyl-1-phenylpyridin-2(1H)-one;

• Molecular Formula:

  C₁₂H₁₁NO

• Molecular Weight:

  185.2218

• Molecular Structure:

  

• Hazard Symbols:

   Xn:Harmful;
  

• Risk Codes:

  R22:;
  

• Safety Description:

  S36:;
  

• Company:

  Wuhan Shuiyixing Chemical Co., Ltd.     [ China ]        

• Contact:

  Mandy

• Tel:

  8615711952876

• Fax:

• Email:

  gear@quality-steroid.com