SUNVIDONE® PI (POVIDONE IODINE)
STRUCTURE & NOMENCLATURE
(C6H9NO)n Mw=(111.1)n
Synonyms: PVP-Iodine complex
CTFA/INCI: PVP-Iodine
CAS No.: [25655-41-8]
DMF Number Assigned: 20921; Date of Submission: October 9, 2007
CHARACTERS
Redish-brown or yelowish-brown amorphous powder or aqueous solution, stable and un-irritating, absolutely soluble in water and alcohol.
SPECIFICATION (USP28/EP5)
Sunvidone PI
PH value(1%) 1.5-5.0
Iodide 6.0%max
Loss on Drying 8.0% max
Sulphated ash 0.1% max
Available iodine 9.0% to 12.0% (on dry basis)
PROPERTIES
● Broad spectrum biocide;
Non-selective germicidal action
Bactericide, fungicide, viricide, sporicide, amebicide, insecticide, nematocide
Lacks the tendency for resistant micro-organisms to develop
Effective in dilute solution
Unparalleled for surface sterilization and in mixed infections
● Detoxified iodine;
Low animal and phytotxicity
Non-irritating to skin and mucous membranes
Non-sensitizing
Does not delay healing or formation of granulation tissue
Non-stringing
Reduced hazard if accidentally ingested
● No detectable vapor pressure;
● Water-soluble;
Ease of formulation
Uniform concentrations
Does not permanently stain
● Film-forming;
Prolonged germicidal action
Adheres to treated surfaces where applied
Color delineates treated area
● Stable comples;
No general odor
No loss of iodine