Priligy, Dapoxetine for Delaying Ejaculation PE Treatment (CAS: 129938-20-1)

• Post Date:

  Apr 29,2015

• Expiry Date:

  Apr 28,2016

• Detailed Description:

  Cas No. :129938-20-1 Quantity: 1000Kilograms
  Specs:SGS
  Price:1 USD Kilograms
  Payment Method: T/T,Western Union,Money Gram
  Detailed Product Description
  
  
  Dapoxetine
  Alias: Priligy
  
  English Synonyms: DAPOXETIN; DAPOXETINE; (S-(+)-N, N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride; Dapoxetine hydrochloride
  
  CAS No: 129938-20-1
  
  
  Assay: 98%
  
  Molecular Formula: C21H23NO HCL
  
  Molecular Weight: 341.88
  
  Packing: 1kg/ Foil Bag
  
  Appearance: White powder, odorless, slightly sweet, soluble in water and alcohol. Can be made into tablets, beverages, wine, capsules and other dosage forms
  
  USES: Treat male premature ejaculation and erectile dysfunction.
  
  Applications:
  
  Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.
  
  
  Treat male premature ejaculation and erectile dysfunction.
  Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
  
  
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  Name Dapoxetine / Priligy
  CAS No. 129938-20-1
  ITEMS
  STANDARD
  RESULTS
  
  Characteristics
  White or almost white crystalline powder
  White crystalline powder
  
  Melting point
  175.0~177.0°C
  174.0~179.0°C
  
  Specific rotatlon
  +128°±3(C=1,CH3OH)
  +128°±3(C=1,CH3OH)
  
  Loss on drying
  ≤0.5%
  0.32%
  
  Heavy metals
  0ppm
  0ppm
  
  Relative substance
  ≤0.1%
  Total impurity
  0.07%
  
  Assay(on drled basis)
  ≥99.5%
  99.61%
  
  Conclusion
  It complies to prescrlbed enterprise standard
  
  
  

• CAS Registry Number:

  129938-20-1

• Synonyms:

  ;DAPOXETINE HCL;Rimonabant 75000;LY-21044;((S)-(+)-N,N-Dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride);(S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride;(1S)-N,N-Dimethyl-3-naphthalen-1-yloxy-1-phenyl-propan-1-amine hydrochloride;(S)-n,n-dimethyl-3-(naphthalene-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride;(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride;N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine hydrochloride (1:1);DL-Dapoxteine HCL;Hydrochloric acid Dapoxetine;S-Dapoxetine hydrochloride;D-Dapoxetine HCL;D-Dapoxetine Hydrochloride;

• Molecular Formula:

  C₂₁H₂₄ClNO

• Molecular Weight:

  341.8744

• Molecular Structure:

  

• Company:

  Hubei Yuancheng Saichuang Technology Co., Ltd.     [ China ]        

• Contact:

  Jeffy ding

• Tel:

  +86-027-50756254

• Fax:

  +86-027-68886696

• Email:

  jeffy@ycphar.com