Raloxifene

• Post Date:

  Apr 08,2018

• Expiry Date:

  Apr 08,2019

• Detailed Description:

  Cas No. :84449-90-1 Specs:White powder
  Price:1 USD Metric Tons
  Payment Method: Western Union,Moneygram,banktransfer,bitcoin
  Product Description:
  CAS: 84449-90-1
  M.F.: C28H27NO4S
  M.W. :473.58
  Purity:99%
  Package:25kg/cardboad drum
  Appearance:light yellow
  
  M.P.: 250-253°C
  
  Raloxifene (marketed as Evista by Eli Lilly and Company) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women.
  
  In 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk. A major adverse effect of tamoxifen is uterine cancer; raloxifene caused fewer cases of uterine cancer. Tamoxifen increased the risk of cataracts, but raloxifene did not. Both groups had more blood clots in veins and the lungs, but that side effect was more common with tamoxifen than raloxifene.On September 14, 2007, the U.S. Food and Drug Administration announced approval of raloxifene for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.
  Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4S.HCl, which corresponds to a molecular weight of 510.05 g/mol. Raloxifene HCl is an off-white to pale-yellow solid that is slightly soluble in water.
  
  SERMs mimic estrogen in some tissues and have anti-estrogen activity in others. Other SERMs, such as Pfizer's lasofoxifene and Wyeth's bazedoxifene are in the later development phases.
  
  
  Usage:
  
  Raloxifene is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.[7] For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.

• CAS Registry Number:

  84449-90-1

• Molecular Formula:

  C₂₈H₂₇NO₄S

• Molecular Weight:

  473.58

• Molecular Structure:

  

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  Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.     [ China ]        

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