Sodium Hyaluronate

• Post Date:

  Oct 15,2014

• Expiry Date:

  Apr 13,2015

• Detailed Description:

  Cas No. :9004-61-9 Payment Method: T/T
  

  1.Discovery of HA:In 1934, Karl Meyer isolated a formerly unknown glycosaminoglycan from the vitreous humor of the bovine eye. It differed from any of the other previously discovered glycosamlnoglycans in that it did not contain sulffur. With its distinctive structure, its function within the body was unique. It was named hyaluronan and further scientific study ensued. At the time of its discovery, the new compound took on two names: hyaluronan when referring to its endogenous synthesis and hyaluronic acid when discussing research conducted outside of the body-huma or animal. Today hyaluronan is comonly referred to as hyaluronic acid, regardless of the context in which it is spoken. 2.Structure of HA:Hyaluronic Acid is linear, unbranched, high molecular weight polysaccharides containing a repeating disaccharide unit (D-glucuronic acid and N-acetyl glucosamine). HA, in its natural state, weighs about from 0.5-3.0 million daltons. Its weight lends itself to high viscosity and excellent lubrication within the body. The other glycosaminoglcans in the body include chondroitin sulfate, keratan sulfate, dermatan sulfate, and heparin sulfate. 3. Distribution of HA:HA widely consists in the extracelluar spaces of animal tissue. Almost kinds of animal tissue contain the different quantity of HA. Today Hyaluronic Acid has been found from skin, cockcomb, brain, vitreum, connective tissue, umbilical cord, human serum, articular fluid, gristle, human urine, cock embryo, oocyte, artery and vein etc. Structural Formula:

  HYALURONIC ACID(Topical Grade)

  Items Specifications Description White powder pH 6.0~7.5 Glucuronic Acid ≥43% Molecular Weight ≥1.00?á106 Transparency(in 0.1%aq.sol.,) ≥99.0% Protein ≤0.1% Loss on Drying ≤10.0% Heavy Metals(Pb) ≤20ppm Arsenic ≤2ppm Nitrogen 3.0~4.0% Kinematic Viscosity ≥40mm2/s Bacteria Count <10cfu/g Mold and Yeast <10cfu/g Staphylococcus Aureus Negative Pseudomonas Aeruginosa Negative Usage Scope:cosmetic,ointment for external application etc. Package:100g/bottle 1kg/bag

  1%HYALURONIC ACID Solution(Topical Grade)

  Items Specifications Description Transparent,colorless pH 6.0~7.5 Glucuronic Acid ≥4.8mg/ml HYALURONIC ACID ≥1.0g/100ml Transparency ≥99.0% Protein ≤0.001% Heavy Metals(Pb) ≤0.2|ìg/ml Arsenic ≤0.02|ìg/ml Intrinsic Viscosity 10000~18000mPa?¤s Bacteria Count <10cfu/g Mold and Yeast <10cfu/g Staphylococcus Aureus Negative Usage Scope:cosmetic,ointment for external application etc. Package:1kg/cask,25kg/cask or package by the request of customer

  HYALURONIC ACID(Food Grade)

  Items Specifications Description White powder pH 6.0~7.5 Glucuronic Acid ≥43% Stake density 0.2~0.4g/cm3 Los on Drying ≤8.0% Heavy Metals(Pb) ≤20ppm Arsenic Measure up to Chinese Pharmacopeia Powerful Heat Remain ≤13.0% Bacteria Count <10cfu/g Mold and Yeast <10cfu/g Staphylococcus Aureus Negative Salmonella Negative Escherichia Coli Negative Usage Scope:Nature health-care food for hairdressing and anti-caducity etc. Package:100g/bottle 1kg/bag

• CAS Registry Number:

  9004-61-9

• Synonyms:

  ;hyaluronan;HA;beta-D-glucopyranuronosyl-(1->3)-(3xi)-2-(acetylamino)-2-deoxy-beta-D-ribo-hexopyranosyl-(1->4)-beta-D-glucopyranuronosyl-(1->3)-(3xi)-2-(acetylamino)-2-deoxy-beta-D-ribo-hexopyranose;beta-D-glucopyranose, O-beta-D-glucopyranuronosyl-(1->3)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-, monosodium salt;sodium (2S,3S,4R,5R,6R)-3-{[(2S,3R,5S,6R)-3-(acetylamino)-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-4,5,6-trihydroxytetrahydro-2H-pyran-2-carboxylate (non-preferred name);(3S,4R,5R,6R)-3-[(2S,3R,5S,6R)-3-acetamido-4-[(2S,3R,4S,6S)-6-carboxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6-[(3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-4,5-dihydroxy-tetrahydropyran-2-carboxylic acid;

• Molecular Formula:

  C₂₈H₄₄N₂O₂₃

• Molecular Weight:

  776.6486

• Molecular Structure:

  

• Company:

  Nova Biotech Shandong Co.,Ltd     [ China ]        

• Contact:

  Mr du

• Tel:

  +86-531-88875246/48/49

• Fax:

  +86-531-88875247

• Email:

  nova@nova-bt.com