Sodium picosulfate

• Post Date:

  Jan 09,2018

• Expiry Date:

  Jul 08,2018

• Detailed Description:

  Cas No. :10040-45-6 Quantity: mass in stockKilograms
  Specs:white powder
  Price:negotiable USD Kilograms
  Payment Method: T/T, Western Union,Moneygram and Bitcoin.
  Product Name: Sodium picosulfate
  Alias: 4,4'-(2-Pyridinylmethylene)bis(phenol)bis(sulfuric acid sodium) salt;DA 1773;DA-1773;LA 391;C13072;Sodium Picosulfate (50 mg);Bisacodyl IMpurity D;SodiuM Picosulphate USP
  CAS NO: 10040-45-6
  Appearance: white powder
  MF: C18H13NO8S2.2Na
  Usage: Delay evacuant
  
  
  Description:
  
  Sodium picosulfate (also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Sodipic Picofast, Laxoberal, Laxoberon, Purg-Odan, Picolax, Guttalax, Namilax, Pico-Salax, PicoPrep, and Prepopik,among others.
  
  Effects
  Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12–24 hours to work, since it works in the colon.
  
  Abdominal cramps and diarrhea are normal effects of picosulfate and should be expected.
  
  The use of sodium picosulfate has also been associated with certain electrolyte disturbances, such as hyponatremia and hypokalemia.Patients are often required to drink large amounts of clear fluids as well as rehydrate to reestablish the electrolyte balance.
  
  Mechanism of action
  Sodium picosulfate is a prodrug.It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridiyl)methane (DPM, BPHM).This compound is a stimulant laxative and increases peristalsis in the gut.
  
  Sodium picosulfate is typically prescribed in a combined formulation with magnesium citrate, an osmotic laxative. This combination is a highly effective laxative, often prescribed to patients for bowel cleansing prior to colonoscopies.
  
  

• CAS Registry Number:

  10040-45-6

• Synonyms:

  ;4,4'-(pyridin-2-ylmethylene)bisphenyl bis (sodiumsulphate);Picosulfate Sodium;Sodium picosulphate;disodium (pyridin-2-ylmethanediyl)dibenzene-4,1-diyl disulfate;

• Molecular Formula:

  C₁₈H₁₃NNa₂O₈S₂

• Molecular Weight:

  481.4073

• Molecular Structure:

  

• Company:

  Hengyang Desen Biotechnology Co., Ltd.     [ China ]        

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