Sorafenib

• Post Date:

  Feb 04,2015

• Expiry Date:

  Feb 04,2016

• Detailed Description:

  Cas No. :284461-73-0 Product name: Sorafenib
  CAS: 284461-73-0
  Molecular formula: C21H16ClF3N4O3
  Molecular weight: 464.83
  Description: Sorafenib (co-developed and co-marketed by Bayer and Onyx Pharmaceuticals as Nexavar), is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced primary liver cancer (hepatocellular carcinoma).
  Sorafenib (a bi-aryl urea) is a small molecular inhibitor of several Tyrosine protein kinases (VEGFR and PDGFR) and Raf kinases (more avidly C-Raf than B-Raf).
  (Protein kinases are overactive in many of the molecular pathways that cause cells to become cancerous. These pathways include Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 and 3 kinases and c Kit the receptor for Stem cell factor. )

• CAS Registry Number:

  284461-73-0

• Synonyms:

  ;4-[4-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide;4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide;4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide 4-methylbenzenesulfonate;Sorafenib base;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea;4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-Pyridinecarboxamide;

• Molecular Formula:

  C₂₈H₂₄ClF₃N₄O₆S

• Molecular Weight:

  637.0266

• Molecular Structure:

  

• Company:

  AUSMAUCO BIOTECH CO., LIMITED     [ China ]        

• Contact:

  john

• Tel:

  +8618060810639

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• Email:

  plantsale@aus-bio.com