Sorafenib tosylate

• Post Date:

  Jul 04,2016

• Expiry Date:

  Jul 04,2017

• Detailed Description:

  Cas No. :475207-59-1
  Chemical Name: 4 - {4 [3 - (4-chloro-3-trifluoromethyl-phenyl) ureide] phenoxy} pyridine-2-carboxamide p-toluenesulfonate
  Product Alias: toluenesulfonic sorafenib mesylate Sorafenib Sorafenib p-toluenesulfonic
  English name: Sorafenib tosylate
  English Synonyms: Sorafenib (Nexavar)
  CAS: 475207-59-1
  Keywords: Sorafenib tosylate, sorafenib tosylate, mesylate Sorafenib, 475207-59-1
  Molecular formula: C21H16ClF3N4O3.C7H8SO3
  Molecular Weight: 637.03
  Appearance: yellow or white crystalline powder
  Melting point: 225-235 ℃
  Loss on drying: Less than 0.5%
  Heavy metals: Less than 10ppm
  Total impurities: less than 1.0%
  Content: 99%
  Packing: 1kg / aluminum foil bag
  Uses: toluenesulfonic Sorafenib is a novel multi-target anticancer drugs, can act simultaneously on tumor cells and tumor blood vessels. It has a dual anti-tumor effects: either by blocking the RAF / MEK / ERK-mediated cell signaling
  
  Pathway directly inhibit the proliferation of tumor cells, but also by inhibiting VEGF and platelet-derived
  Health growth factor (PDGF) receptors and block the formation of tumor angiogenesis, indirectly inhibit the growth of tumor cells.

• CAS Registry Number:

  475207-59-1

• Synonyms:

  ;SORAFENIB-D3;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea Tolsylate;Sorafenib TsOH salt;

• Molecular Formula:

  C₂₁H₁₆ClF₃N₄O₃·C₇H₈SO

• Molecular Weight:

  637.03

• Molecular Structure:

  

• Company:

  Wuhan Yuancheng Gongchuang Technology Co     [ China ]        

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  jorcelyn

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