Sorafenib tosylate

Post Date:
Jun 07,2016
Expiry Date:
Dec 04,2016
Detailed Description:
Cas No. :475207-59-1 Sorafenib tosylate Basic information
Product Name: Sorafenib tosylate
Synonyms: SORAFENIB TOSYLATE;Sorafenib & its intermediates;Sorafinib mesylate;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;Sorafenib Tosylate(Bay 43-9006,Nexavar);2-PyridinecarboxaMide, 4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-, 4-Methylbenzenesulfonate;Sorafenib Tosylate (Nexavar);Sorafenib (Nexavar)
CAS: 475207-59-1
MF: C21H16ClF3N4O3.C7H8SO3
MW: 637.03

Sorafenib tosylate Usage And Synthesis
Usage Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.
Usage Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively
CAS Registry Number:
475207-59-1
Synonyms:
;SORAFENIB-D3;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea Tolsylate;Sorafenib TsOH salt;
Molecular Formula:
C₂₁H₁₆ClF₃N₄O₃·C₇H₈SO
Molecular Weight:
637.03
Molecular Structure:

Offter to Sell