Sunifiram

• Post Date:

  Jun 26,2018

• Expiry Date:

  Dec 23,2018

• Detailed Description:

  Cas No. :314728-85-3 Sunifiram
  Sunifiram
  1. Introduction
  Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric
  modulator of AMPA receptors, and has nootropic effects in animal studies with significantly
  higher potency than piracetam. A number of related compounds are known, the best known
  being unifiram (DM-232)
  
  This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.
  
  2. Specification (Manufacturer supply directly)
  Product Name Sunifiram (DM-235)
  Synony 1-benzoyl-4-propanoylpiperazine
  Molecular Formul C14H18N2O2
  Molecular Weight 246.304
  CAS No. 314728-85-3
  Purity 99.8%
  Melting point 94.5°C-95.5°C
  Appearance Off-white to white crystalline powder
  
  
  3. Function
  1.Sunifiram activates AMPA-mediated neurotransmission.
  2.Enhancing LTP in a bell-shaped dose-response relationship.
  3.Sunifiram aids in the release of acetylcholine in the cerebral cortex.
  4. Packing &Storage
  
  Packaging Detail
  25kg/drum or as per customer's requirement
  Storage
  Store in a well-closed container away from moisture
  Shelf Life
  2 years if sealed and store away from direct sun light.
  Delivery Detail
  Within 7 working days after order confirmation
  
  Buy Sunifiram raw online:
  If it is possible, you are welcomed to our company.if you have questions for us,
  Don't hesitate to contact via
  ​1. send mails to daisy@chembj.com
  
  >> We love hearing from you for any of questions or queries you may have.

• CAS Registry Number:

  314728-85-3

• Synonyms:

  Sunifiram;DM-235;1-Benzoyl-4-(1-oxopropyl)piperazine

• Molecular Formula:

  C₁₄H₁₈N₂O₂

• Molecular Weight:

  246.31176

• Molecular Structure:

  

• Company:

  Hubei Yuancheng Saichuang technology Co.1td     [ China ]        

• Contact:

  daisy

• Tel:

  86-027-50755978

• Fax:

• Email:

  daisy@chembj.com