Tetrodotoxin TTX (with citrate)

• Post Date:

  Mar 18,2013

• Expiry Date:

  Mar 18,2014

• Detailed Description:

  Cas No. :4368-28-9 Quantity: 5*1mg
  Specs:>98 %
  Price:517 USD Metric Tons
  Tetrodotoxin (with citrate) is a Na+ channel blocker in excitable tissues, Highly selective, reversible sodium channel blocker.
  References:
  1.Kao (1972) Pharmacology of tetrodotoxin and saxitoxin. Fed.Proc. 31 1117. PMID: 5032475.
  2.Catterall WA Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Annu Rev Pharmacol Toxicol 20:15-43 (1980). Read more (PubMed: 6247957)
  3.Kao (1986) Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. Ann.N.Y.Acad.Sci. 479 52. PMID: 2434008.
  4.Narahashi T et al. Recent advances in the study of mechanism of action of marine neurotoxins. Neurotoxicology 15:545-54 (1994). Read more (PubMed: 7854588)
  5.Gleitz et al (1996) The protective action of tetrodotoxin and (±)-kavain on anaerobic glycolysis, ATP content and intracellular Na+ and Ca2+ of anoxic brain vesicles. Neuropharmacology 35 1743. PMID: 9076753.
  6.Hille, B. (2001) Ion Channels in Excitable Membranes (Third Edition) Chapter 3.
  
  
  

• CAS Registry Number:

  4368-28-9

• Synonyms:

  ;(1R,5S,6R,7S,9S,11S,12S,13S,14S)-3-amino-5,9,12,13,14-pentahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene (non-preferred name);(1R,5S,6R,7S,9S,11S,12S,13S,14R)-3-amino-5,9,12,13,14-pentahydroxy-14-(hydroxymethyl)-8,10-dioxa-2-aza-4-azoniatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene (non-preferred name);(1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1^7,11.0^1,6]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name);

• Molecular Formula:

  C₁₁H₁₇N₃O₈

• Molecular Weight:

  319.268

• Molecular Structure:

  

• Company:

  AffixScientific     [ United States ]        

• Contact:

  Rob Martin

• Tel:

  +1-510-936-6647

• Fax:

  +1-510-936-6647

• Email:

  rob@affixscientific.com