The Second Generation of Aromatase Inhibitors and Have Good Effect; CAS: 107868-30-4

• Post Date:

  Dec 20,2017

• Expiry Date:

  Dec 20,2018

• Detailed Description:

  Cas No. :107868-30-4 Quantity: 1Kilograms
  Specs:USP/BP/EP/CP
  Price:1 USD Kilograms
  Payment Method: T/T
  Synonyms:6-methylenandrosta-1,4-diene-3,17-dione;androsta-1,4-diene-6-methylene-3,17-dione;6-METHYLENEANDROSTA-1,4-DIENE-3,17-DIONE;6-Methylene-androsta-1,4-diene-3,17-dione;AROMASIN;EXALAMIDE;6-methylenandrost-1,4-diene-3,17-dione;6-Methyleneandrosta-1,4-diene-3,17-dione;
  CAS 107868-30-4
  MF C20H24O2
  MW 296.40300
  Quality 296.17800
  PSA 34.14000
  LogP 4.02950
  Physical and chemical properties
  Appearance and properties white to pale yellow crystalline powder
  density 1.13 g/cm3
  melting point 155.13 ° C
  boiling point 453.7DHS C at 760 mmHg
  flash point 169 DHS C
  refractive index 1.572
  storage conditions Store in the original container in a cool dark place
  steam pressure 2.02 e-08 mmHg at 25 ° C
  Introduction of compounds
   (trade name Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.
  use
   is the second generation aromatase inhibitors, its role is different from the anti-estrogen drugs, it can combine with aromatase and irreversible inactivated, thus reduce circulating estrogen levels rapidly and consistently, inhibits tumor growth. The role of the drug than the same kind of aromatase inhibitors f beauty is better, and less toxicity. More importantly, this product does not exist the former oral coupling faults occur, can be made into a variety of dosage forms. Clinically for the treatment of metastatic breast cancer and used as adjuvant therapy of early breast cancer, curative effect and good tolerance, relatively few side effects.

• CAS Registry Number:

  107868-30-4

• Synonyms:

  ;Exemestan;6-Methylenandrosta-1,4-diene-3,17-dione;10,13-Dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-;6-methylideneandrosta-1,4-diene-3,17-dione;(8ξ,9ξ,14ξ)-6-methylideneandrosta-1,4-diene-3,17-dione;Exemestane(Aromasin);Exemestone;

• Molecular Formula:

  C₂₀H₂₄O₂

• Molecular Weight:

  296.4034

• Molecular Structure:

  

• Company:

  WUHAN DONG KANG YUAN TECHNOLOGY CO., LTD.     [ China ]        

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