everytihng about Coluracetam

• Post Date:

  Apr 13,2016

• Expiry Date:

  Apr 13,2017

• Detailed Description:

  Cas No. :135463-81-9 Payment Method: within 24 hours after receipt of the payment
  Coluracetam
  Keywords:nootropics Piracetam,Aniracetam,Pramiracetam,Oxiracetam, Coluracetam,Phenylpiracetam smart drugs Piracetam,Aniracetam, Pramiracetam,Oxiracetam,Coluracetam,Phenylpiracetam hot sale nootropics
  CAS No:135463-81-9
  Purity:99%
  Appearance:white crystalline powder
  Package:1kg/bag.
  
  Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.
  Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.
  
  
  

• CAS Registry Number:

  135463-81-9

• Synonyms:

  N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

• Molecular Formula:

  C₁₉H₂₃N₃O₃

• Molecular Weight:

  341.4042

• Molecular Structure:

  

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