pentadecapeptide BPC 157

• Post Date:

  Dec 12,2017

• Expiry Date:

  Jun 10,2018

• Detailed Description:

  Price:1 USD Metric Tons
  Product Details
  Basic Info.
  Model NO.:CAS: pentadecapeptide BPC 157
  
  Function:Blood System Agents
  Certification:GMP
  
  pentadecapeptide BPC 157 Grade Standard:Medicine Grade
  pentadecapeptide BPC 157 Type:Chemical Reagent
  
  pentadecapeptide BPC 157 State:Solid
  pentadecapeptide BPC 157 Volatile:Not Volatile
  
  Product Name:Pentadecapeptide Bpc 157
  pentadecapeptide BPC 157 Appearance:White Solid Powder
  
  pentadecapeptide BPC 157 Assay:99%
  pentadecapeptide BPC 157 Package:2mg/vial
  
  Abstract
  Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H2O2 stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway.
  
  peptides
  T-A001 MGF
  T-A002 PEG MGF
  T-A003 CJC-1295 with DAC
  T-A004 CJC-1295 without DAC/GRF 1-29
  T-A005 PT-141
  T-A006 MT-1
  T-A007 MT-2
  T-A008 GHRP-2
  T-A008 GHRP-2
  T-A009 GHRP-6
  T-A009 GHRP-6
  T-A010 Ipamorelin
  T-A011 Hexarelin
  T-A012 Sermorelin
  T-A013 Oxytocin
  T-A014 TB500
  T-A015 pentadecapeptide BPC 157
  T-A016 HGH 176-191
  T-A017 Triptorelin
  T-A018 Tesamorelin
  T-A020 Gonadorelin
  T-A020 Gonadorelin
  T-A021 DSIP
  T-A022 Selank
  40077-57-4 Aviptadil Acetate
  79561-22-1 Alarelin Acetate
  112568-12-4 Antide Acetate
  β-Amyloid (1-42),human Amyloid β-Protein (Human, 1-42)
  58-49-1 Angiotensin Acetate
  CJC-1295 Acetate
  69-25-0 Eledoisin Acetate
  32780-32-8 PT141 Acetate
  128270-60-0 Bivalirudin Trifluoroacetate
  57773-65-5 Deslorelin Acetate
  16789-98-3 Desmopressin Acetate
  60731-46-6 Elcatonin Acetate
  38234-21-8 Fertirelin Acetate
  159519-65-0 Enfuvirtide Acetate (T-20)
  148031-34-9 Eptifibatide
  141758-74-9 Exenatide Acetate (Exendin-4)
  106612-94-6 GLP-1 (7-37) Acetate
  71447-49-9 Gonadorelin Acetate
  158861-67-7 GHRP-2 Acetate
  87616-84-0 GHRP-6 Acetate
  140703-51-1 Hexarelin
  16941-32-5 Glucagon(1-29)(Human)
  50-57-7 Lysipressin Acetate
  121062-08-6 Melanotan-II (MT-II)
  114471-18-0 Nesiritide Acetate (BNP-32)
  83150-76-9 Octreotide Acetate
  83930-13-6 GRF human Acetate
  50-56-6 Oxytocin Acetate
  3397-23-7 Ornipressin Acetate
  196078-30-5 Pramlintide Acetate
  105184-37-0 Splenopentin Acetate
  17034-35-4 Secretin Acetate
  86168-78-7 Sermorelin Acetate
  38916-34-6 Somatostatin Acetate
  16960-16-0 Tetracosactide Acetate
  14636-12-5 Terlipressin Acetate
  62304-98-7 Thymosin α1 Acetate
  77591-33-4 Thymosin β4 Acetate
  57773-63-4 Triptorelin Acetate
  

• Company:

  yuancheng         

• Contact:

  +86-18872220676

• Tel:

  +86-18872220676

• Fax:

• Email:

  john@ycphar.com