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paclitaxel CAS: 33069-62-4

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  Post Date: Mar 30,2013
  Expiry Date: Mar 30,2014
  Detailed Description: Cas No. :33069-62-4 Quantity: 20Metric Tons
Payment Method: TT/LC/DP

paclitaxel CAS: 33069-62-4

Product Name:paclitaxel

Another Name:5 β, 20- epoxy -1, 2 α, 4β, 7β, 10α, 13 - six hydroxyl taxane -11- allyl -9- ketone -4, 10- two acetate -2- benzoate -13[ ( 2 ' R, 3 ' S ) -N- benzoyl -3- phenylisoserine ester

CAS: 33069-62-4

Molecular Weight:853.92

Molecular Formula:C47H51NO14

[ source ] products is the dried root of Taxus plants of Taxus, leaves and bark.
[ size ] 99.5% content
[ physical ] white crystal powder. Odorless, tasteless. Insoluble in water, soluble in chloroform, acetone and other organic solvents.
Function: through the clinical study ofⅡ - Ⅲ, paclitaxel is mainly suitable for ovarian cancer and breast cancer, lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma, brain tumors have certain curative effect.


Items of analysis Specification
Characters A white crystalline powder, odorless, tasteless
Solubility Dissolved in methanol, ethanol or chloroform, slightly soluble in ether, insoluble in water.
Optical rotation -48°~-56°
Identification
UV:Should have a maximum absorption at 227nm wavelength
HPLC:Paclitaxel peak retention time and standard control retention time should be consistent
solution appearance Clear and colorless
Related impurities
7-Epitaxol ≤ 0.5%
Deacetyltaxol ≤0.5%
Single unknown impurity ≤0.1%
Other total impurities ≤1.5%
Solvent Residue
Methanol ≤3000ppm
Methyl cyanide≤410ppm
Acetone ≤5000ppm
Methylene chloride ≤600ppm
Chloroform ≤60ppm
Loss on drying ≤1.0%
Assay 98.0%~102.0%
Heavy metal ≤ 20ppm
Bacterial endotoxins≤0.4 EU/mg


  CAS Registry Number:

33069-62-4

  Synonyms: ;7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.;taxal;taxol a;Taxol;
  Molecular Formula: C47H51NO14
  Molecular Weight: 853.9061
  Molecular Structure: 33069-62-4 Paclitaxel
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R41:;
  Safety Description: S26:;
S36/37/39:;
S45:;

  Company: Hubei Yuancheng Pharmaceutical Co., ltd     [ China ]        
  Contact: Lupin
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