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paclitaxel CAS:33069-62-4

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  Post Date: Mar 31,2013
  Expiry Date: Mar 31,2014
  Detailed Description: Cas No. :33069-62-4 Quantity: 20Metric Tons
Payment Method: TT/LC/DP
paclitaxel CAS:33069-62-4

Product Name:paclitaxel

Another Name:5 β, 20- epoxy -1, 2 α, 4β, 7β, 10α, 13 - six hydroxyl taxane -11- allyl -9- ketone -4, 10- two acetate -2- benzoate -13[ ( 2 ' R, 3 ' S ) -N- benzoyl -3- phenylisoserine ester


CAS:33069-62-4

Molecular Weight:853.92

Molecular Formula:C47H51NO14

[ source ] products is the dried root of Taxus plants of Taxus, leaves and bark.
[ size ] 99.5% content
[ physical ] white crystal powder. Odorless, tasteless. Insoluble in water, soluble in chloroform, acetone and other organic solvents.
Function: through the clinical study ofⅡ - Ⅲ, paclitaxel is mainly suitable for ovarian cancer and breast cancer, lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma, brain tumors have certain curative effect.

Characters
A white crystalline powder, odorless, tasteless
Solubility
Dissolved in methanol, ethanol or chloroform, slightly soluble in ether, insoluble in water.
Conforms
Optical rotation -48o~-56o Identification
UV:Should have a maximum
absorption at 227nm wavelength
Conforms
HPLC:Paclitaxel peak retention time and standard control retention time should be consistent
Solution appearance Clear and colorless Conforms
Related impurities
7-Epitaxol ≤ 0.5%
Deacetyltaxol ≤0.5%
Single unknown impurity ≤0.1%
Other total impurities ≤1.5%
Solvent Residue
Methanol ≤3000ppm
Methyl cyanide ≤410ppm
Acetone ≤5000ppm
Methylene chloride ≤600ppm
Chloroform ≤60ppm
Loss on drying ≤1.0%
Assay 98.0%~102.0%
Heavy metal ≤ 20ppm
Bacterial
endotoxins ≤0.4 EU/mg

  CAS Registry Number:

33069-62-4

  Synonyms: ;7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.;taxal;taxol a;Taxol;
  Molecular Formula: C47H51NO14
  Molecular Weight: 853.9061
  Molecular Structure: 33069-62-4 Paclitaxel
  Hazard Symbols:  Xn:Harmful;
  Risk Codes: R40:;
R41:;
  Safety Description: S26:;
S36/37/39:;
S45:;

  Company: Hubei Yuancheng Pharmaceutical Co., ltd     [ China ]        
  Contact: Lupin
  Tel: +86-27-68886724
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