pentadecapeptide BPC 157
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| Post Date: | Dec 12,2017 |
| Expiry Date: | Jun 10,2018 |
| Detailed Description: |
Price:1 USD Metric Tons Product Details Basic Info. Model NO.:CAS: pentadecapeptide BPC 157 Function:Blood System Agents Certification:GMP pentadecapeptide BPC 157 Grade Standard:Medicine Grade pentadecapeptide BPC 157 Type:Chemical Reagent pentadecapeptide BPC 157 State:Solid pentadecapeptide BPC 157 Volatile:Not Volatile Product Name:Pentadecapeptide Bpc 157 pentadecapeptide BPC 157 Appearance:White Solid Powder pentadecapeptide BPC 157 Assay:99% pentadecapeptide BPC 157 Package:2mg/vial Abstract Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H2O2 stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway. peptides T-A001 MGF T-A002 PEG MGF T-A003 CJC-1295 with DAC T-A004 CJC-1295 without DAC/GRF 1-29 T-A005 PT-141 T-A006 MT-1 T-A007 MT-2 T-A008 GHRP-2 T-A008 GHRP-2 T-A009 GHRP-6 T-A009 GHRP-6 T-A010 Ipamorelin T-A011 Hexarelin T-A012 Sermorelin T-A013 Oxytocin T-A014 TB500 T-A015 pentadecapeptide BPC 157 T-A016 HGH 176-191 T-A017 Triptorelin T-A018 Tesamorelin T-A020 Gonadorelin T-A020 Gonadorelin T-A021 DSIP T-A022 Selank 40077-57-4 Aviptadil Acetate 79561-22-1 Alarelin Acetate 112568-12-4 Antide Acetate β-Amyloid (1-42),human Amyloid β-Protein (Human, 1-42) 58-49-1 Angiotensin Acetate CJC-1295 Acetate 69-25-0 Eledoisin Acetate 32780-32-8 PT141 Acetate 128270-60-0 Bivalirudin Trifluoroacetate 57773-65-5 Deslorelin Acetate 16789-98-3 Desmopressin Acetate 60731-46-6 Elcatonin Acetate 38234-21-8 Fertirelin Acetate 159519-65-0 Enfuvirtide Acetate (T-20) 148031-34-9 Eptifibatide 141758-74-9 Exenatide Acetate (Exendin-4) 106612-94-6 GLP-1 (7-37) Acetate 71447-49-9 Gonadorelin Acetate 158861-67-7 GHRP-2 Acetate 87616-84-0 GHRP-6 Acetate 140703-51-1 Hexarelin 16941-32-5 Glucagon(1-29)(Human) 50-57-7 Lysipressin Acetate 121062-08-6 Melanotan-II (MT-II) 114471-18-0 Nesiritide Acetate (BNP-32) 83150-76-9 Octreotide Acetate 83930-13-6 GRF human Acetate 50-56-6 Oxytocin Acetate 3397-23-7 Ornipressin Acetate 196078-30-5 Pramlintide Acetate 105184-37-0 Splenopentin Acetate 17034-35-4 Secretin Acetate 86168-78-7 Sermorelin Acetate 38916-34-6 Somatostatin Acetate 16960-16-0 Tetracosactide Acetate 14636-12-5 Terlipressin Acetate 62304-98-7 Thymosin α1 Acetate 77591-33-4 Thymosin β4 Acetate 57773-63-4 Triptorelin Acetate |
| Company: | yuancheng |
| Contact: | +86-18872220676 |
| Tel: | +86-18872220676 |
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| Email: | john@ycphar.com |
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