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Cas No. :84380-01-8
α-Arbutin(Alpha Arbutin) is a new type of hydroquinone glucoside with an α-glucosyl bond.
as a skin-lightening ingredient of cosmetics, α-Arbutin has strong inhibiting effect on human tyrosinase. Indeed, the enzyme is involved in synthesis of melanin which causes freckles and suntan.
α-Arbutin is a cosmetic ingredient that customers can use safely and comfortably. For your use of α-Arbutin, you can receive not only quality assurance but also data concerning safety and efficacy as well as support with respect to α-Arbutin-related applications.
Mechanism of Melanogenesis Inhibition of α-Arbutin:
α-Arbutin and β- Arbutin:
Sample |
Mushroom |
Human |
| IC50 |
IC50 |
| α-Arbutin |
Not detected |
1.8 - 2.1 mM |
| Arbutin (β) |
8 mM |
> 30 mM |
Trade Name α-Arbutin
Chemical name 4-Hydroxyphenyl-α-D-glucopyranoside
CAS No. 84380-01-8
ELINCS No. 440-470-8
INCI name Alpha-Arbutin
Molecular Formula C12H16O7
Molecular Weight 272.25
Chemical Structure 
Specifications
Appearance White powder
Purity ≥99% (HPLC)
Melting point 202-212℃
Specific rotation [α]20D +180±6°
Solution Clear
Loss on drying Less than 1.0%
Microbiological
Specified pathogens None
Microbial count ≤100 CFU/g
Fungus ≤50 CFU/g
Safety
To be safe for cosmetic use. The available data do not indicate any risks.
Storage
α-Arbutin (Alpha-Arbutin) should be stored in the original sealed pouchs protected from light and humidity in a clean area at a temperature of between 10 and 30°C.
If stored under the recommended conditions, α-Arbutin remains stable for 3 years.
Packing
1kg PVC+aluminum pouch
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