ParamChem was a NSF sponsored initiative to develop an integrated cyber environment to address the simulation needs of molecular sciences. While it ran out of funding before meeting its ambitious end-goal of releasing a fully-integrated GUI-driven infrastructure for automatic parameter optimization, the technologies developed as part of the project represent substantial advancements in the field; please visit our technology page to access the CGenFF program, the lsfitpar parameter fitting software etc. All text below this point pertains to the original project that is now defunct, and only serves historical purposes.